US2019151418A1PendingUtilityA1

Combination of calcium-phosphate-containing porous composite and pth

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Assignee: TOYO BOSEKIPriority: Apr 8, 2016Filed: Feb 24, 2017Published: May 23, 2019
Est. expiryApr 8, 2036(~9.7 yrs left)· nominal 20-yr term from priority
Inventors:Shinji KamakuraSatoru NakajouAtsushi IwaiFumihiko KajiiHidenori TanakaKazuo Sasaki
A61P 5/18A61P 19/08A61L 27/3847A61L 27/54A61K 47/02A61K 9/08A61K 9/0024A61K 47/42A61L 2430/02A61K 9/10A61K 33/42A61K 9/0014A61K 9/0019A61L 31/123A61L 31/044A61L 27/12A61K 38/29A61L 27/56A61L 31/146
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Claims

Abstract

Provided is a means effective in bone regeneration or bone augmentation. Provided is a porous composite containing octacalcium phosphate and parathyroid hormone.

Claims

exact text as granted — not AI-modified
1 . A porous composite comprising octacalcium phosphate and parathyroid hormone. 
     
     
         2 . The porous composite of  claim 1 , having a moisture content of 5 wt. % or less. 
     
     
         3 . The porous composite of  claim 1 , which is for use in bone regeneration or bone augmentation. 
     
     
         4 . The porous composite of  claim 1 , further comprising collagen. 
     
     
         5 . The porous composite of  claim 1 , wherein the parathyroid hormone is teriparatide. 
     
     
         6 . A method of producing a second porous composite containing octacalcium phosphate and parathyroid hormone, the method comprising
 adding the parathyroid hormone to a first porous composite containing the octacalcium phosphate.   
     
     
         7 . The production method of  claim 6 , further comprising freeze-drying the second porous composite. 
     
     
         8 . The production method of  claim 6 , wherein the first porous composite further contains collagen. 
     
     
         9 . The production method of  claim 6 , wherein the parathyroid hormone is teriparatide.

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