US2019125636A1PendingUtilityA1

Oral Care Composition

Assignee: COLGATE PALMOLIVE COPriority: Dec 24, 2012Filed: Dec 19, 2018Published: May 2, 2019
Est. expiryDec 24, 2032(~6.4 yrs left)· nominal 20-yr term from priority
A61K 8/21A61K 8/24A61K 8/19A61K 2800/30A61Q 11/00A61K 8/27A61K 8/365
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Claims

Abstract

The present invention relates to an oral care composition with a high water content which has improved robustness towards microbial challenge. The oral care composition includes compositions comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof.

Claims

exact text as granted — not AI-modified
1 . An aqueous oral care composition comprising from 0.125 wt % to 0.75 wt % of a water soluble source of stannous ions, wherein the composition comprises at least 50 wt % water and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof. 
     
     
         2 . The oral care composition of  claim 1 , wherein the composition comprises from 0.125 wt % to 0.5 wt % of the source of stannous ions. 
     
     
         3 . The oral care composition of  claim 2 , wherein the composition comprises from 0.125 wt % to 0.3 wt % of the source of stannous ions. 
     
     
         4 . The oral care composition of  claim 2 , wherein the composition comprises from 0.15 wt % to 0.3 wt % of the source of stannous ions. 
     
     
         5 . The oral care composition of  claim 1 , wherein the source of stannous ions is stannous chloride. 
     
     
         6 . The oral care composition of  claim 1 , wherein the composition comprises from 50 wt % to 65 wt % water. 
     
     
         7 . The oral care composition of  claim 6 , wherein the composition comprises from 52 wt % to 60 wt % water. 
     
     
         8 . The oral care composition of  claim 6 , wherein the composition comprises from 54 wt % to 55 wt % water. 
     
     
         9 . The oral care composition of  claim 1 , further comprising a fluoride ion source selected from the group consisting of sodium fluoride, potassium fluoride, potassium monofluorophosphate, sodium monofluorophosphate, ammonium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, an amine fluoride, ammonium fluoride, and combinations thereof. 
     
     
         10 . The oral care composition of  claim 1 , further comprising a source of zinc ions. 
     
     
         11 . The oral care composition of  claim 10 , wherein the source of zinc ions comprises zinc oxide, zinc citrate, or mixtures thereof. 
     
     
         12 . The oral care composition of  claim 11 , wherein the composition comprises zinc citrate in an amount of from 1.5 wt % to 2.5 wt %. 
     
     
         13 . The oral care composition of  claim 11 , wherein the composition comprises zinc oxide in an amount of from 0.5 wt % to 1.5 wt %. 
     
     
         14 . The oral care composition of  claim 1 , wherein the composition is a toothpaste, a tooth gel, a mouthrinse, a cream or an ointment. 
     
     
         15 . The oral care composition of  claim 1 , wherein the composition is free of additional antibacterial or preservative agents. 
     
     
         16 . The oral care composition of  claim 1 , wherein the composition has improved robustness towards microbial challenge. 
     
     
         17 . A method of improving the robustness of an oral care composition containing at least 50 wt % water towards microbial challenge comprising adding to the oral care composition a water soluble source of stannous ions, wherein the source of stannous ions is present in the oral care composition at a concentration of from 0.1 wt % to 0.75 wt %, and wherein the source of stannous ions is selected from the group consisting of stannous chloride, stannous pyrophosphate, stannous formate, stannous acetate, stannous gluconate, stannous lactate, stannous tartrate, stannous oxalate, stannous malonate, stannous citrate, stannous ethylene glyoxide, and mixtures thereof. 
     
     
         18 . The method of  claim 17 , wherein the composition comprises from 0.15 wt % to 0.3 wt % of the source of stannous ions. 
     
     
         19 . The method of  claim 17 , wherein the source of stannous ions is stannous chloride. 
     
     
         20 . The method of  claim 17 , wherein the composition comprises from 50 wt % to 60 wt % water.

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