Feed additive composition
Abstract
A feed additive composition comprising a direct fed microbial (DFM), in combination with a xylanase (e.g. endo-1,4-β-d-xylanase) and a β-glucanase (and optionally a further fibre degrading enzyme), wherein the DFM is selected from the group consisting of an enzyme producing strain; a C5 sugar-fermenting strain; a short-chain fatty acid-producing strain; a fibrolytic, endogenous microflora-promoting strain; or combinations thereof. The DFM may be selected from the group consisting of: Bacillus subtilis AGTP BS3BP5, Bacillus subtilis AGTP BS442, B. subtilis AGTP BS521, B. subtilis AGTP BS918, Bacillus subtilis AGTP BS1013, B. subtilis AGTP BS1069, B. subtilis AGTP 944, B. pumilus AGTP BS 1068 or B. pumilus KX11-1, Enterococcus faecium ID7, Propionibacterium acidipropionici P169, Lactobacillus rhamnosus CNCM-I-3698, Lactobacillus farciminis CNCM-I-3699, a strain having all the characteristics thereof, any derivative or variant thereof, and combinations thereof and the further fibre degrading enzyme may be selected from the group consisting of a cellobiohydrolase (E.C. 3.2.1.176 and E.C. 3.2.1.91), a β-glucosidase (E.C. 3.2.1.21), a β-xylosidase (E.C. 3.2.1.37), a feruloyl esterase (E.C. 3.1.1.73), an α-arabinofuranosidase (E.C. 3.2.1.55), a pectinase (e.g. an endopolygalacturonase (E.C. 3.2.1.15), an exopolygalacturonase (E.C. 3.2.1.67) or a pectate lyase (E.C. 4.2.2.2)), or combinations thereof.
Claims
exact text as granted — not AI-modified1 . (canceled)
2 . A method for improving the performance of a subject or for improving digestibility of a raw material in a feed, or for improving nitrogen retention, or for improving feed conversion ratio (FCR), or for improving weight gain in a subject, or for improving feed efficiency in a subject, or for shifting the fermentation process in the subject's gastrointestinal tract towards the production of butyric acid and/or propionic acid, the method comprising administering a direct fed microbial (DFM) to the subject, in combination with a xylanase and a β-glucanase, wherein the DFM is selected from the group consisting of an enzyme producing strain; a C5 sugar-fermenting strain; a short-chain fatty acid-producing strain; a fibrolytic, endogenous microflora-promoting strain; and combinations thereof.
3 . The method of claim 2 , wherein the DFM is an enzyme producing strain.
4 . The method of claim 2 , wherein the DFM is a C5 sugar-fermenting strain.
5 . The method of claim 2 , wherein the DFM is a short-chain fatty acid-producing strain.
6 . The method of claim 2 , wherein the DFM is a fibrolytic, endogenous microflora-promoting strain.
7 . The method of claim 2 , wherein the DFM is at least one strain of bacterium selected from the group consisting of the following genera: Bacillus, Enterococcus, Lactobacillus, Propionibacterium and combinations thereof.
8 . The method of claim 2 , wherein the DFM is at least one strain selected from the Bacillus genus.
9 . The method of claim 2 , wherein the DFM is selected from the group consisting of: Bacillus subtilis AGTP BS3BP5, Bacillus subtilis AGTP BS442, Bacillus subtilis AGTP BS521, Bacillus subtilis AGTP BS918, Bacillus subtilis AGTP BS1013, Bacillus subtilis AGTP BS1069, Bacillus subtilis AGTP 944 , B. pumilus AGTP BS 1068 or B. pumilus KX11-1, Enterococcus faecium ID7, Propionibacterium acidipropionici P169, Lactobacillus rhamnosus CNCM-I-3698, Lactobacillus farciminis CNCM-I-3699, and combinations thereof.
10 . The method of claim 2 , wherein the DFM is a viable bacterium.
11 . The method of claim 2 , wherein the direct fed microbial is in the form of an endospore.
12 . The method of claim 2 , wherein the xylanase is an endo-1,4-β-d-xylanase.
13 . (canceled)
14 . The method of claim 2 , wherein the method comprises administering to a subject a direct fed microbial (DFM), in combination with a xylanase and a β-glucanase and a further fibre degrading enzyme.
15 . The method of claim 14 , wherein the further fibre degrading enzyme is selected from the group consisting of a cellobiohydrolase (E.C. 3.2.1.176 and E.C. 3.2.1.91), a β-glucosidase (E.C. 3.2.1.21), a β-xylosidase (E.C. 3.2.1.37), a feruloyl esterase (E.C. 3.1.1.73), an α-arabinofuranosidase (E.C. 3.2.1.55), a pectinase (e.g. an endopolygalacturonase (E.C. 3.2.1.15), an exopolygalacturonase (E.C. 3.2.1.67) or a pectate lyase (E.C. 4.2.2.2)), or combinations thereof.
16 . The method of claim 15 , wherein the further fibre degrading enzyme is selected from the group consisting of a cellobiohydrolase (E.C. 3.2.1.176 and E.C. 3.2.1.91), a β-glucosidase (E.C. 3.2.1.21) or combinations thereof.
17 . The method of claim 2 , further comprising administering at least one vitamin and/or at least one mineral to the subject.
18 - 25 . (canceled)
26 . The method of claim 2 , wherein the DFM is selected from the group consisting of Bacillus subtilis, B. licheniformis, B. amyloliquefaciens , and B. pumilus.Join the waitlist — get patent alerts
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