Pain Medicine Combination and Uses Thereof

Abstract

Embodiments disclosed herein describe, amongst other things, dosage forms, compounds, compositions, pharmaceutical compositions that can be used in the treatment of, for example, pain and pain related disorders or to produce analgesia.

1 - 51 . (canceled) 
     
     
         52 . A non-sustained release pharmaceutical composition formulated for simultaneous administration consisting essentially of:
 dextromethorphan, or a pharmaceutically acceptable salt thereof;   quinidine, or a pharmaceutically acceptable salt thereof, and   morphine, or a pharmaceutically acceptable salt thereof,   wherein the ratio of morphine, or a pharmaceutically acceptable salt thereof, to dextromethorphan, or a pharmaceutically acceptable salt thereof, to quinidine, or a pharmaceutically acceptable salt thereof, is about 1:1:1 (wt:wt:wt).   
     
     
         53 . The pharmaceutical composition of  claim 52 , wherein the dextromethorphan is dextromethorphan hydrobromide monohydrate. 
     
     
         54 . The pharmaceutical composition of  claim 52 , wherein the quinidine is quinidine gluconate or quinidine sulfate. 
     
     
         55 . The pharmaceutical composition of  claim 52 , wherein the morphine is morphine sulfate. 
     
     
         56 . The pharmaceutical composition of  claim 52 , wherein the composition does not have a sequestered opioid antagonist. 
     
     
         57 . A method of treating pain in a subject in need thereof, the method comprising administering to the subject the pharmaceutical composition of  claim 52 .