Peptides for use in promoting transport of glucose

Abstract

A natural glucose transport promoting peptide comprising a glucose transport promoting fragment of a protein selected from SEQUENCE ID NO's: 1 to 6, and a composition comprising a plurality of glucose transport promoting peptides, is described. Also disclosed is the use of the peptides and compositions in improving muscle status in a mammal, especially promoting recovery of muscle following exercise or enhancing physical performance.

1 . A comestible powder comprising a peptide having 8-50 amino acids and comprising a fragment of a protein of SEQUENCE ID NO: 1 selected from the group consisting of: SEQUENCE ID NO's 7 to 20, 181, 190-195, 204, 207 and 216-218. 
     
     
         2 . A comestible powder according to  claim 1  in which the fragment is selected from the group consisting of: SEQUENCE ID NO: 7 or 13. 
     
     
         3 .- 40 . (canceled) 
     
     
         41 . A comestible powder according to  claim 1 , including all of the peptides of SEQUENCE ID NO's 7 to 20. 
     
     
         42 . A comestible powder according to  claim 1 , in which the comestible powder is a nutritional supplement or a food additive. 
     
     
         43 . A method of improving glycaemic management in a mammal comprising a step of orally administering to the mammal a comestible powder of  claim 1 , in which glycaemic management in the mammal is improved by one or more of lowering plasma blood glucose levels, treating or preventing hyperglycaemia, increasing post prandial insulin secretion, regulating glucose homeostasis, and reducing or attenuating insulin resistance. 
     
     
         45 . A method according to  claim 43 , in which glycaemic management in the mammal is improved by lowering plasma blood glucose levels. 
     
     
         46 . A method according to  claim 43 , in which the mammal is a human with pre-diabetes or diabetes.