US2019076422A1PendingUtilityA1

Use of an h4 agonist molecule for the treatment of idiopathic pulmonary fibrosis

Assignee: H4 ORPHAN PHARMAPriority: Mar 18, 2016Filed: Mar 17, 2017Published: Mar 14, 2019
Est. expiryMar 18, 2036(~9.6 yrs left)· nominal 20-yr term from priority
A61K 9/28A61K 9/48A61K 9/20A61K 9/006A61K 9/0095A61K 9/0056A61P 11/00A61K 31/4741A61K 9/0053
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Claims

Abstract

The present invention concerns the use of an H4 agonist molecule against histamin, enantiomers of (AMINO-7 TRIETHOXY-4,5,6 OXO-1 DIHYDRO-1,3 ISOBENZOFURANNYL-3)-1 METHOXY-8 METHYL-METHYLENEDIOXY-6,7 TETRAHYDRO-,2,3,4 ISOQUINOLINE or tritoqualine, for the treatment of idiopathic pulmonary fibrosis.

Claims

exact text as granted — not AI-modified
1 - 3 . (canceled) 
     
     
         4 . A substance comprising:
 an agonist activity on the histamine H4 receptor for its use in the treatment of idiopathic pulmonary fibrosis, wherein it is comprised of an isomer or of a mixture of isomers of 7-Amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl- 1,3 -dioxolo[4,5-g]isoquinolin-5-yl) phthalide, or tritoqualine.   
     
     
         5 . Substance for its use according to  claim 4 , wherein it inhibits TGFβ. 
     
     
         6 . Substance for its use according to  claim 4 , wherein it is packaged under different dosage forms: soft capsules, tablets, capsules, syrup, gel. 
     
     
         7 . Substance for its use according to  claim 5 , wherein it is packaged under different dosage forms: soft capsules, tablets, capsules, syrup, gel.

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