US2019062843A1PendingUtilityA1

Micro-rna biomarkers and methods of using same

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Assignee: BIOMIRNA HOLDINGS LTDPriority: Feb 7, 2011Filed: Mar 21, 2018Published: Feb 28, 2019
Est. expiryFeb 7, 2031(~4.5 yrs left)· nominal 20-yr term from priority
Inventors:Gabriella SozziUgo PastorinoMattia Boeri
A61P 35/00A61P 3/00C12Q 2600/158C12Q 2600/118C12Q 1/6886C12Q 2600/178G16B 30/00
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Claims

Abstract

A procedure and an apparatus are described for identifying individuals at risk of pulmonary tumour and/or for diagnosing a pulmonary tumour using the study of levels of expression of miRNA in the blood or another biological fluid. Also described are a method and a compound for reducing or eliminating a risk of pulmonary tumour by rebalancing the miRNAs that are underexpressed or overexpressed.

Claims

exact text as granted — not AI-modified
1 . A method comprising:
 determining the level of expression of at least two miRNA from the miRNA listed in Tables Ia, Ic, IIa, IIc, Va, Vc, VIa, or VIc in a biological sample from a subject, and   comparing the level of expression of said miRNA from said sample from said subject to the level of expression of said miRNA from a control biological sample.   
     
     
         2 .- 43 . (canceled)

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