US2019038684A1PendingUtilityA1

Equol-producing lactic acid bacteria-containing composition

Assignee: OTSUKA PHARMA CO LTDPriority: Jun 30, 2003Filed: Oct 12, 2018Published: Feb 7, 2019
Est. expiryJun 30, 2023(expired)· nominal 20-yr term from priority
A61P 3/06A61P 5/32A61P 5/30A61P 9/12A61P 35/00A61P 15/00A61P 15/12A61P 19/10A61P 19/00A23L 33/135A61K 35/744C12P 17/06A23C 9/123A61K 35/747A23C 11/106C12R 1/46A23Y 2220/00A23L 11/65A61K 35/74A61K 35/66C12R 2001/46C12N 1/205A23V 2400/11
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Claims

Abstract

An equol-producing lactic acid bacteria-containing composition comprises, as an essential component thereof, a lactic acid bacterial strain belonging to the genus Lactococcus having an ability to utilize at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein, and dihydrodaidzein to produce equol. Such a composition is effective for the prevention and alleviation of malaise inclusive of climacteric disturbance in middle-aged and elderly women for which no effective prophylactic method or alleviating means has heretofore been available.

Claims

exact text as granted — not AI-modified
1 . An equol-producing lactic acid bacteria-containing composition comprising, as an essential component thereof, a lactic acid bacterial strain belonging to the genus  Lactococcus  having an ability to utilize at least one daidzein compound selected from the group consisting of daidzein glycosides, daidzein, and dihydrodaidzein to produce equol. 
     
     
         2 . The composition according to  claim 1 , wherein said lactic acid bacterial strain belonging to the genus  Lactococcus  is  Lactococcus garvieae.    
     
     
         3 . The composition according to  claim 2 , wherein said lactic acid bacterial strain belonging to  Lactococcus  is  Lactococcus  20-92 deposited under FERM BP-10036. 
     
     
         4 . The composition according to  claim 1  further comprising at least one member selected from the group consisting of daidzein compounds and daidzein compound-containing ingredients. 
     
     
         5 . The composition according to  claim 4 , wherein the daidzein compound-containing ingredient is soybean flour or soy milk 
     
     
         6 . The composition according to  claim 4  which is in the form of a beverage or a milk product. 
     
     
         7 . The composition according to  claim 4  further comprising equol. 
     
     
         8 . The composition according to  claim 7  which is in the form of a fermentation product of soy milk. 
     
     
         9 . A method of producing equil comprising the step of letting a lactic acid bacterial strain belonging to the genus  Lactococcus  having an ability to utilize a daidzein compound to produce equol act on at least one member selected from the group consisting of daidzein compounds and daidzein compound-containing ingredients. 
     
     
         10 . The method according to  claim 9 , wherein said lactic acid bacterial strain belonging to the genus  Lactococcus  is  Lactococcus garvieae.    
     
     
         11 . The method according to  claim 10  wherein said lactic acid bacterial strain belonging to the genus  Lactococcus  is  Lactococcus  20-92 deposited under FERM BP-10036. 
     
     
         12 . The method according to  claim 9 , wherein the daidzein compound-containing ingredient is soybean flour or soy milk. 
     
     
         13 . A lactic acid bacterial strain belonging to the genus  Lactococcus  as deposited under FERM BP-10036.

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