US2019022136A1PendingUtilityA1

Micron-sized gold, kit comprising said gold and its use as a non-toxic immune suppressor as well as gold implants

Assignee: BERLOCK APSPriority: Jan 9, 2013Filed: Sep 19, 2018Published: Jan 24, 2019
Est. expiryJan 9, 2033(~6.5 yrs left)· nominal 20-yr term from priority
Inventors:Gorm Danscher
A61P 25/28A61P 17/06A61K 47/36A61P 29/00A61K 33/24A61K 9/0019A61P 37/02A61P 17/02A61K 33/242C08L 5/08A61L 2420/04A61L 2300/802A61L 2300/102A61L 27/32A61L 2400/12A61L 2400/06A61L 27/306A61L 27/54A61K 9/14
36
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Claims

Abstract

Sterile micron-sized gold particles contained in capped vials, a kit of part including the vial and a liquid capable of suspending the particles, as well as their preparation, medical devices or medicaments prepared by their preparation as well as uses thereof in treating inflammation. Also, gold coated implants preferably for use in combination with the medical devices.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 - 29 . (canceled) 
     
     
         30 . A method of treating inflammatory conditions within a human or animal, the method comprising the steps of:
 injecting a liquid compatible with a within a human or animal body, the liquid having micron-sized gold particles or gold flakes in suspension, into the human or animal body.   
     
     
         31 . The method of  claim 30  wherein the micron-sized gold particles or gold flakes cannot be phagocytozed by macrophages. 
     
     
         32 . The method of  claim 31 , wherein the liquid is injected within a human or animal joint. 
     
     
         33 . The method of  claim 31 , further comprising:
 dissolucytosing gold ions from the micron-sized gold particles or gold flakes outside of the macrophages, the gold ions localized proximate to the micron-sized gold particles or gold flakes, the gold ions operable to therapeutically reduce aseptic inflammation.   
     
     
         34 . The method of  claim 31 , wherein the inflammatory condition is selected from the group consisting of arthrose, multiple sclerosis, Alzheimer's disease, psoriasis, eczema, autoimmune diseases and inflammation related conditions, wounds, as well as cosmetic conditions such as wrinkles. 
     
     
         35 . The method of  claim 31 , wherein the treating inflammatory conditions within a human or animal, comprises prophylactically treating inflammatory conditions within a human or animal. 
     
     
         36 . The method of  claim 35 , wherein the prophylactically treating inflammatory conditions within a human or animal, comprises prophylactically treating arthrose of weight bearing joints within a human or animal. 
     
     
         37 . A kit comprising:
 a capped vial, said capped vial being penetrable by a syringe, wherein the capped vial contains:
 micron-sized gold particles or gold flakes, wherein the micron-sized gold particles or gold flakes cannot be phagocytozed by macrophages; and 
 a liquid, compatible with the human body, operable to maintain the micron-sized gold particles or gold flakes in suspension for at least one minute at a temperature of approximately 25° C. 
   
     
     
         38 . The kit of  claim 37 , wherein the liquid is delivered to the capped vial by the syringe. 
     
     
         39 . The kit of  claim 37 , wherein the liquid has a viscosity of about 1-110 cP. 
     
     
         40 . The kit of  claim 37 , wherein the liquid comprises medical grade hyaluronic acid. 
     
     
         41 . The kit of  claim 37 , wherein the liquid comprises synovial fluid withdrawn from a patient. 
     
     
         42 . The kit of  claim 37 , further comprising a bead operable to facilitate distribution and suspension of the micron-sized gold particles or gold flakes within the liquid. 
     
     
         43 . A medical device operable to mitigate inflammatory conditions within a human or animal, the medical device comprising:
 a liquid compatible with a human or animal body, the liquid comprising micron-sized gold particles or gold flakes in suspension, wherein the micron-sized gold particles or gold flakes cannot be phagocytozed by macrophages.   
     
     
         44 . The medical device of  claim 43 , wherein the liquid is operable to be injected within a human or animal joint. 
     
     
         45 . The medical device of  claim 43 , wherein the micron-sized gold particles or gold flakes dissolucytose gold ions from the micron-sized gold particles or gold flakes outside of the macrophages, the gold ions localized proximate to the micron-sized gold particles or gold flakes, the gold ions operable to therapeutically reduce aseptic inflammation proximate to the micron-sized gold particles or gold flakes.

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