Gelatin particles, method for producing gelatin particles, gelatin particle-containing cell, and method for producing gelatin particle-containing cell

Abstract

Disclosed herein are gelatin particles including gelatin, wherein when a major-axis length of dried gelatin particles is defined as a and a major-axis length of gelatin particles after swelling treatment obtained by immersing the dried gelatin particles in water at 40° C. under an atmospheric pressure for 60 minutes is defined as b, swelling degree represented by b/a is 1.0 or more but 10.0 or less, and wherein the gelatin particles after swelling treatment have a particle diameter of 1.0 nm or more but 5.0 μm or less. The gelatin particles are easily taken up by cells themselves.

1 . Gelatin particles, wherein when a major-axis length of dried gelatin particles is defined as a and a major-axis length of gelatin particles after swelling treatment obtained by immersing the dried gelatin particles in water at 40° C. under an atmospheric pressure for 60 minutes is defined as b, swelling degree represented by b/a is 1.0 or more but 10.0 or less, and wherein the gelatin particles after swelling treatment have a particle diameter of 1.0 nm or more but 5.0 μm or less. 
     
     
         2 . The gelatin particles according to  claim 1 , wherein the dried gelatin particles have an aspect ratio of 1.0 or more but 1.4 or less. 
     
     
         3 . The gelatin particles according to  claim 1 , wherein the major-axis length b of the gelatin particles after swelling treatment is 2.0 μm or less. 
     
     
         4 . The gelatin particles according to  claim 1 , further comprising a contrast medium. 
     
     
         5 . The gelatin particles according to  claim 1 , wherein the gelatin has been crosslinked. 
     
     
         6 . A method for producing gelatin particles, comprising discharging droplets of a liquid containing melted gelatin into an atmosphere in a heating tube or a drying chamber whose difference in temperature from the droplets is 235° C. or less and drying the droplets to obtain gelatin particles. 
     
     
         7 . The method for producing gelatin particles according to  claim 6 , wherein the droplets are discharged from a nozzle of an inkjet head. 
     
     
         8 . A gelatin particle-containing cell, wherein the gelatin particles according to  claim 1  are contained inside a cell membrane. 
     
     
         9 . A method for producing a gelatin particle-containing cell, comprising adding the gelatin particles according to  claim 1  and a cell to a liquid to allow the gelatin particles to be taken up inside a cell membrane of the cell by action of the cell. 
     
     
         10 . The gelatin particles according to  claim 2 , wherein the major-axis length b of the gelatin particles after swelling treatment is 2.0 μm or less. 
     
     
         11 . The gelatin particles according to  claim 2 , further comprising a contrast medium. 
     
     
         12 . The gelatin particles according to  claim 2 , wherein the gelatin has been crosslinked. 
     
     
         13 . A gelatin particle-containing cell, wherein the gelatin particles according to  claim 2  are contained inside a cell membrane. 
     
     
         14 . A method for producing a gelatin particle-containing cell, comprising adding the gelatin particles according to  claim 2  and a cell to a liquid to allow the gelatin particles to be taken up inside a cell membrane of the cell by action of the cell. 
     
     
         15 . The gelatin particles according to  claim 3 , further comprising a contrast medium. 
     
     
         16 . The gelatin particles according to  claim 3 , wherein the gelatin has been crosslinked. 
     
     
         17 . A gelatin particle-containing cell, wherein the gelatin particles according to  claim 3  are contained inside a cell membrane. 
     
     
         18 . A method for producing a gelatin particle-containing cell, comprising adding the gelatin particles according to  claim 3  and a cell to a liquid to allow the gelatin particles to be taken up inside a cell membrane of the cell by action of the cell. 
     
     
         19 . The gelatin particles according to  claim 4 , wherein the gelatin has been crosslinked. 
     
     
         20 . A gelatin particle-containing cell, wherein the gelatin particles according to  claim 4  are contained inside a cell mem