Oral Care Compositions and Methods of Use

Abstract

Disclosed herein are oral care compositions comprising hemp seed oil and caprylyl glycol. In certain embodiments, the oral care composition optionally further comprises one or more ingredients selected from hyaluronic acid and aloe vera. Methods of making and using the compositions are also provided.

1 . A mouthrinse comprising:
 hemp seed oil;   caprylyl glycol; and   an orally acceptable base.   
     
     
         2 . The mouthrinse of  claim 1 , wherein said composition has a moisture retention capacity of at least 4.8, as measured in an n vitro moisture retention capacity assay. 
     
     
         3 . The mouthrinse of  claim 2 , wherein said hemp seed oil is present at a concentration from 0.8 to 1.2%, by weight of the composition. 
     
     
         4 . The mouthrinse of  claim 3 , wherein said hemp seed oil is present at a concentration of 1.0% by weight of the composition. 
     
     
         5 . The mouthrinse of  claim 3 , wherein said caprylyl glycol is present at a concentration of 0.15 to 0.35%, by weight of the composition. 
     
     
         6 . The mouthrinse of  claim 5 , wherein said caprylyl glycol is present at a concentration of 0.25%, by weight of the composition. 
     
     
         7 . The mouthrinse of  claim 5 , further comprising aloe vera. 
     
     
         8 . The mouthrinse of  claim 7 , wherein said aloe vera is present at a concentration of 0.15 to 0.35%, by weight of the composition. 
     
     
         9 . The mouthrinse of  claim 8 , wherein said aloe vera is present at a concentration of 0.25%, by weight of the composition. 
     
     
         10 . The mouthrinse of  claim 5 , further comprising hyaluronic acid. 
     
     
         11 . The mouthrinse of  claim 10 , wherein said hyaluronic acid is present at a concentration of 0.01 to 0.1%, by weight of the composition. 
     
     
         12 . The mouthrinse of  claim 11 , wherein said hyaluronic acid is present at a concentration of 0.05%, by weight of the composition. 
     
     
         13 . A mouthrinse comprising
 a) hemp seed oil at a concentration from 0.8 to 1.2%, by weight of the composition;   b) caprylyl glycol at a concentration of 0.15 to 0.35% by weight of the composition;   c) optionally aloe vera at a concentration of 0.15 to 0.35%, by weight of the composition; and   d) optionally hyaluronic acid at a concentration of 0.01 to 0.1%, by weight of the composition.   
     
     
         14 . The mouthrinse of  claim 13 , having a moisture retention capacity of at least 4.8, as measured in an in vitro moisture retention capacity assay. 
     
     
         15 . A method to improve oral health comprising applying an effective amount of the oral composition of any of the preceding claims set forth above to the oral cavity of a subject in need thereof. 
     
     
         16 . The method of  claim 15 , wherein improving oral health may be selected from one or more of the following:
 a. reduce or inhibit formation of dental caries;   b. reduce, repair or inhibit early enamel lesions;   c. reduce or inhibit demineralization and promote remineralization of the teeth;   d. reduce hypersensitivity of the teeth;   e. reduce or inhibit gingivitis;   f. promote healing of sores or cuts in the mouth;   g. reduce levels of acid producing bacteria;   h. increase relative levels of arginolytic bacteria;   i. inhibit microbial biofilm formation in the oral cavity;   j. raise and/or maintain plaque pH at levels of at least pH 5.5 following sugar challenge;   k. reduce plaque accumulation;   l. treat, relieve or reduce dry mouth;   m. whiten teeth;   n. enhance systemic health, including cardiovascular health;   o. reduce erosion of the teeth;   p. immunize the teeth against cariogenic bacteria and their effects;   q. clean the teeth and oral cavity;   r. reduce inflammation;   s. increase anti-oxidant levels;   t. reduce oral discomfort;   u. increase lubrication;   v. reduce tissue friction due to drying; and   w. increase tissue hydration.