US2018312566A1PendingUtilityA1
Fc FUSION HIGH AFFINITY IgE RECEPTOR ALPHA-CHAIN
Est. expiryFeb 20, 2035(~8.5 yrs left)· nominal 20-yr term from priority
C07K 16/18C12N 15/09C07K 19/00C07K 14/70535C07K 14/705A61K 38/16C07K 2319/30A61K 38/00A61K 47/68
49
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Claims
Abstract
Provided is an Fc fusion high affinity IgE receptor α-chain having excellent stability at low pH. An Fc fusion protein comprising: (i) a high affinity IgE receptor α-chain; and (ii) an Fc region of IgG1, wherein a linker fragment region between the (i) and the (ii) is the amino acid sequence shown in SEQ ID NO: 2.
Claims
exact text as granted — not AI-modified1 . An Fc fusion protein comprising:
(i) a high affinity IgE receptor α-chain; and (ii) an Fc region of IgG1, wherein a linker fragment region between the (i) and the (ii) is the amino acid sequence shown in SEQ ID NO: 2.
2 . The Fc fusion protein according to claim 1 , which is a dimer.
3 . The Fc fusion protein according to claim 2 , wherein cysteine residues in the linker fragment region form three disulfide bonds.
4 . A pharmaceutical composition comprising, as an active ingredient, the Fc fusion protein according to claims 1 .Join the waitlist — get patent alerts
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