Ingestion-related biofeedback and personalized medical therapy method and system

Abstract

A system including a sensor, a mobile device, and a computer system is disclosed. The sensor is configured to detect physiologic data from the body of the patient. The mobile device includes a patient data input device. The computer system, communicatively coupled to the mobile device, includes a patient record indicating: patient data comprising a plurality of patient activities, and detected physiological data received from the sensor via the mobile device. The computer system is configured to identify an unhealthy physiological data value from the detected physiological data of the patient record, correlate the unhealthy physiological data value to a patient activity of the patient data, select a therapeutic recommendation to address the unhealthy physiological data value, and transmit the selected therapeutic recommendation to the patient, via the mobile device, at a future time associated with the patient activity correlated to the unhealthy physiological data value.

1 - 20 . (canceled) 
     
     
         21 . A system, comprising:
 a sensor coupled to a body of a patient, wherein the sensor is configured to detect physiologic data from the body of the patient and wirelessly transmit the physiologic data;   an electronic communication device associated with the patient, wherein the electronic communication device comprises a patient input device; and   a computer system communicatively coupled to the electronic communication device, wherein the computer system comprises:
 a patient record associated with the patient, wherein the patient record indicates:
 patient activity data comprising a plurality of proposed activities of the patient, wherein each proposed activity is associated with a proposed time to engage in its associated proposed activity; and 
 detected physiological data received from the sensor via the electronic communication device; 
 
   wherein the computer system is configured to:
 compare the detected physiological data of the patient record to a range of healthy values, associated with the physiological data, to identify an unhealthy physiological data value; 
 correlate the identified unhealthy physiological data value to a proposed activity of the patient activity data; 
 select a therapeutic recommendation to bring the identified unhealthy physiological data value within the range of healthy values associated with the physiological data; and 
 transmit the selected therapeutic recommendation to the patient, via the electronic communication device, at a future proposed time associated with the correlated proposed activity. 
   
     
     
         22 . The system of  claim 21 , wherein one or more than one of the plurality of proposed activities of the patient activity data is received via the patient input device. 
     
     
         23 . The system of  claim 21 , wherein the plurality of proposed activities are associated with at least one of a work task, a physical exercise, a stress inducing event, a hobby, a recreational activity, a meal consumption, a liquid ingestion, a social interaction, or an erotic act. 
     
     
         24 . The system of  claim 21 , wherein the patient record of the computer system further indicates:
 attestation data received via the patient input device, wherein the attestation data comprises at least one attestation associated with a change to a proposed activity of the plurality of proposed activities; and   
       wherein the computer system is further configured to:
 correlate the identified unhealthy physiological data value to a changed activity associated with the attestation data; and 
 transmit the selected therapeutic recommendation to the patient, via the electronic communication device, at a future proposed time associated with the correlated changed activity. 
 
     
     
         25 . The system of  claim 21 , wherein the computer system is further configured to:
 compare the detected physiological data to the plurality of proposed activities of the patient activity data to identify patterns between unhealthy physiological data values and proposed activities of the patient; and   transmit a therapeutic recommendation to the patient, via the electronic communication device, prior to a proposed activity having an identified pattern to an unhealthy physiological data value.   
     
     
         26 . The system of  claim 21 , wherein the computer system is further configured to:
 compare the detected physiological data to the plurality of proposed activities of the patient activity data to identify patterns between unhealthy physiological data values and routine activities of the patient; and   transmit a therapeutic recommendation to the patient, via the electronic communication device, prior to a routine activity having an identified pattern to an unhealthy physiological data value.   
     
     
         27 . The system of  claim 26 , wherein the routine activity is a stress-inducing activity. 
     
     
         28 . The system of  claim 21 , further comprising:
 a plurality of ingestible event markers (IEMs), wherein each IEM is stably associated with a medication, wherein each IEM is configured to generate ingestion data and wirelessly transmit the ingestion data after contact with bodily fluid of the patient at a target physiological site, and wherein the ingestion data comprises an identification of the medication and a time of the ingestion;   wherein the patient record of the computer system further indicates:
 a prescribed medication of the patient, wherein the prescribed medication is associated with a medication schedule including prescribed times to administer the prescribed medication; and 
 ingestion data received from one or more than one IEM ingested by the patient via the electronic communication device, wherein the one or more than one ingested IEM comprises the prescribed medication; and 
   wherein the computer system is further configured to:
 determine, based on the ingestion data of the patient record, that the prescribed medication has not been administered at a prescribed time of the medication schedule that has passed; and 
 transmit to the electronic communication device, after a designated time period since the passed prescribed time, a message to remind the patient to administer the prescribed medication. 
   
     
     
         29 . The system of  claim 28 , wherein the patient record of the computer system further indicates:
 attestation data received via the patient input device, wherein the attestation data comprises at least one attestation associated with an administered medication; and   
       wherein the computer system is further configured to:
 determine, based on the attestation data, that the prescribed medication has not been administered at the prescribed time of the medication schedule that has passed. 
 
     
     
         30 . The system of  claim 21 , wherein the patient record further indicates:
 a prescribed behavior of the patient, wherein the prescribed behavior is associated with a behavior schedule including prescribed times to perform or to avoid the prescribed behavior; and   attestation data received via the patient input device, wherein the attestation data comprises at least one attestation associated with a behavior performed or a behavior avoided; and   
       wherein the computer system is further configured to:
 determine, based on the attestation data, that the prescribed behavior has not been attested to at a prescribed time of the behavior schedule that has passed; and 
 transmit to the electronic communication device, after a designated time period since the passed prescribed time, a message to remind the patient to perform or to avoid the prescribed behavior. 
 
     
     
         31 . The system of  claim 21 , wherein the electronic communication device is further configured to communicate the selected therapeutic recommendation to the patient. 
     
     
         32 . The system of  claim 21 , wherein the therapeutic recommendation is selected from the group consisting essentially of a medicine prescription adjustment, a meditation practice, a relaxation practice, a physical exercise, a period of sleep, a procedural change, a therapy change and a dietary adjustment. 
     
     
         33 . The system of  claim 21 , wherein the physiological data comprises at least one of a heart rate, a blood pressure, a respiration rate, a respiration intensity, or electrical skin conductivity. 
     
     
         34 . The system of  claim 21 , wherein the therapeutic recommendation is further selected based at least partly on genetic information descriptive of the patient. 
     
     
         35 . The system of  claim 21 , wherein the therapeutic recommendation is further selected based at least partly on additional patient information selected from the group consisting essentially of lifestyle data, patient adherence information, behavioral information, emotional information and diagnostic test information. 
     
     
         36 . A system, comprising:
 a sensor coupled to a body of a patient, wherein the sensor is configured to detect physiologic data from the body of the patient;   a mobile device associated with the patient, wherein the mobile device comprises a patient data input device; and   a computer system communicatively coupled to the mobile device, wherein the computer system comprises:
 a patient record associated with the patient, wherein the patient record indicates:
 patient data comprising a plurality of patient activities; and 
 detected physiological data received from the sensor via the mobile device; 
 
   wherein the computer system is configured to:
 identify an unhealthy physiological data value from the detected physiological data of the patient record; 
 correlate the unhealthy physiological data value to a patient activity of the patient data; 
 select a therapeutic recommendation to address the unhealthy physiological data value; and 
 transmit the selected therapeutic recommendation to the patient, via the mobile device, at a future time associated with the patient activity correlated to the unhealthy physiological data value. 
   
     
     
         37 . The system of  claim 36 , wherein the plurality of patient activities are associated with at least one of a work task, a physical exercise, a stress inducing event, a hobby, a recreational activity, a meal consumption, a liquid ingestion, a social interaction, or an erotic act. 
     
     
         38 . The system of  claim 36 , wherein the computer system is further configured to:
 compare the detected physiological data to the plurality of patient activities of the patient data to identify patterns between unhealthy physiological data values and routine activities of the patient; and   transmit a therapeutic recommendation to the patient, via the mobile device, prior to a routine activity having an identified pattern to an unhealthy physiological data value.   
     
     
         39 . The system of  claim 36 , further comprising:
 a plurality of ingestible event markers (IEMs), wherein each IEM is stably associated with a medication, wherein each IEM is configured to generate ingestion data and wirelessly transmit the ingestion data after contact with bodily fluid of the patient at a target physiological site, and wherein the ingestion data comprises an identification of the medication and a time of the ingestion;   wherein the patient record of the computer system further indicates:
 a prescribed medication of the patient, wherein the prescribed medication is associated with a medication schedule including prescribed times to administer the prescribed medication; and 
 ingestion data received from one or more than one IEM ingested by the patient via the mobile device, wherein the one or more than one ingested IEM comprises the prescribed medication; and 
   wherein the computer system is further configured to:
 determine, based on the ingestion data of the patient record, that the prescribed medication has not been administered at a prescribed time of the medication schedule that has passed; and 
 transmit to the mobile device, after a designated time period since the passed prescribed time, a message to remind the patient to administer the prescribed medication. 
   
     
     
         40 . The system of  claim 36 , wherein the patient record further indicates:
 a prescribed behavior of the patient, wherein the prescribed behavior is associated with a behavior schedule including prescribed times to perform or to avoid the prescribed behavior; and   attestation data received via the patient data input device, wherein the attestation data comprises at least one attestation associated with a behavior performed or a behavior avoided; and   
       wherein the computer system is further configured to:
 determine, based on the attestation data, that the prescribed behavior has not been attested to at a prescribed time of the behavior schedule that has passed; and 
 transmit to the mobile device, after a designated time period since the passed prescribed time, a message to remind the patient to perform or to avoid the prescribed behavior.