Method for the Treatment of Neuropathies and/or Neuropathic Pain

Abstract

A method of treating a subject having neuropathies and/or neuropathic pain, that includes administering a pharmaceutical composition or dietary supplement having, as the active ingredients, Curcuma longa extract, acetyl ester of L-carnitine and alpha-lipoic acidA is described.

What is claimed is: 
     
         1 . A method of treating a subject having neuropathies and/or neuropathic pain, comprising administering a pharmaceutical composition or dietary supplement comprising, as the active ingredients,  Curcuma longa  extract, acetyl ester of L-carnitine and alpha-lipoic acid,
 wherein the active ingredients are present in a therapeutically effective amount for treating neuropathies and/or neuropathic pain.   
     
     
         2 . The method of  claim 1 , wherein said  Curcuma longa  extract has a curcumin titre of about 95%. 
     
     
         3 . The method of  claim 1 , wherein the pharmaceutical composition or dietary supplement is in a dosage form comprising from 350 to 500 mg of acetyl ester of L-carnitine, from 250 to 400 mg of alpha-lipoic acid, and from 100 to 500 mg of  Curcuma longa  extract. 
     
     
         4 . The method of  claim 1 , wherein the pharmaceutical composition or dietary supplement is in a dosage form comprising about 400 mg of acetyl ester of L-carnitine, about 300 mg of alpha-lipoic acid, and about 150 mg of  Curcuma longa  extract. 
     
     
         5 . The method of  claim 1 , wherein the pharmaceutical composition or dietary supplement is in an oral dosage form. 
     
     
         6 . The method of  claim 1 , wherein the neuropathy is selected from the group consisting of peripheral neuropathy, inflammatory post-traumatic neuropathy, lumbosciatic syndrome, diabetic metabolic neuropathy, mechanical neuropathy due to nerve entrapment and compression, carpal tunnel syndrome, chemotherapy-induced neuropathy, antiretroviral therapy-induced neuropathy, zoster virus neuropathy, brachial nerve neuropathy due to vaccination. 
     
     
         7 . The method of  claim 1 , wherein the pharmaceutical composition or dietary supplement is-for use in oral administration, wherein said use comprises administration of from 350 to 1000 mg/day of acetyl ester of L-carnitine, from 250 to 800 mg/day of alpha-lipoic acid, and from 100 to 1000 mg/day of  Curcuma longa  extract. 
     
     
         8 . The method of  claim 1 , wherein the pharmaceutical composition or dietary supplement further comprises one or more vitamins selected from the group consisting of vitamin C, vitamin E, vitamin B1, vitamin B2, vitamin B6 and vitamin B12. 
     
     
         9 . The method of  claim 1 , wherein the pharmaceutical further comprises pharmaceutically acceptable excipients and/or binders and/or vehicles.