US2018207230A1PendingUtilityA1
Autoclavable suspensions of cyclosporin a form 2
Est. expiryNov 15, 2031(~5.3 yrs left)· nominal 20-yr term from priority
A61P 37/08A61P 37/06A61P 27/04A61P 27/02A61K 9/0048C07K 1/306C07K 7/645A61K 47/32A61K 38/13A61K 47/36A61K 47/38
52
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Claims
Abstract
Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with such formulations.
Claims
exact text as granted — not AI-modifiedWhat is claimed is:
1 . A method of making a formulation of cyclosporin A, the method comprising the steps of
a) dissolving cyclosporin A form 2 in solution; b) autoclaving the solution; c) adding a vehicle selected from carboxymethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, hyaluronic acid, polyvinylpyrrolidone, Carbopol Ultrez 10NF, and Pluronic F127.
2 . A method of making a formulation of cyclosporin A, the method comprising the steps of
a) dissolving in solution a vehicle selected from carboxymethyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose, hyaluronic acid, polyvinylpyrrolidone, Carbopol Ultrez 10NF, and Pluronic F127; b) adding to the solution cyclosporin A Form 2; c) autoclaving the resulting mixture.Join the waitlist — get patent alerts
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