System and Method for Assisted Partitioning of Body Conduits

Abstract

A treatment strategy for treatment of elevated pressure in a body conduit, such as a pulmonary vein, with a prosthetic partitioning device for placement in and/or about pulmonary veins is described, as well as delivery systems, and strategies for use thereof. A control device is configured to transmit signals to the prosthetic device to effectuate the repetitive transition between a first, less restricted flow configuration and a second, restricted flow configuration are described. A sensor device may be provided for monitoring physiological parameters of the patient, and can provide signals to the control device for effectuating the transition between the first and second configuration.

1 - 26 . (canceled) 
     
     
         27 . A delivery system for delivery of prosthetic partitioning device for partitioning the flow in a body conduit of a patient comprising: (a) a prosthetic partitioning device configured for coaxial attachment to a body conduit and movable between a first configuration permitting a less restricted fluid flow therethrough and a second configuration permitting a more restricted fluid flow therethrough, the prosthetic partitioning device effectuating transition between the first configuration and the second configuration in response to activity in the patient's body; (b) an elongated catheter configured for insertion into the body conduit having a prosthetic conduit-carrying portion; and (c) a protective sheath configured to cover the prosthetic partitioning device during insertion into the body conduit. 
     
     
         28 . The delivery system according to  claim 27 , wherein the prosthetic partitioning device is configured for placement on the exterior of the body conduit. 
     
     
         29 . The delivery system according to  claim 27 , wherein the prosthetic partitioning device is configured for placement within the interior of the body conduit. 
     
     
         30 . The delivery system according to  claim 27 , wherein the prosthetic partitioning device comprises an expandable component. 
     
     
         31 . The delivery system according to  claim 27 , wherein the prosthetic partitioning device, the catheter, and the protective sheath are configured for use in open surgical procedures. 
     
     
         32 . The delivery system according to  claim 27 , wherein the prosthetic partitioning device, the catheter, and the protective sheath are configured for use in laparoscopic procedures. 
     
     
         33 . The delivery system according to  claim 27 , wherein the prosthetic partitioning device, the catheter, and the protective sheath are configured for use in percutaneous procedures. 
     
     
         34 . A prosthetic partitioning device configured for coaxial attachment about a body conduit comprising: an expandable balloon element movable between a less expanded configuration permitting a less restricted fluid flow therethrough and a more expanded configuration permitting a more restricted fluid flow therethrough. 
     
     
         35 . The prosthetic partitioning device according to  claim 34 , wherein the expandable balloon element comprises a plurality of expandable balloon elements configured for sequential expansion of said plurality of balloon elements. 
     
     
         36 . A prosthetic partitioning device configured for coaxial attachment about a body conduit comprising: (a) a clamping element comprising a first clamping arm and a second clamping arm and movable between a spaced apart configuration permitting a less restricted fluid flow therethrough and an approximated configuration permitting a more restricted fluid flow therethrough; and (b) an actuator attached to one of the first clamping arm and the second clamping arm for effectuating the transition between the spaced apart configuration and the approximated configuration. 
     
     
         37 . The prosthetic partitioning device according to  claim 36 , wherein the clamping element comprises a plurality of pairs of clamping arms configured for sequential transition of said clamping arms. 
     
     
         38 . The prosthetic partitioning device according to  claim 36 , wherein the actuator is electromechanical. 
     
     
         39 . The prosthetic partitioning device according to  claim 36 , wherein the actuator is electromagnetic. 
     
     
         40 . The prosthetic partitioning device according to  claim 36 , wherein the actuator is hydraulic. 
     
     
         41 . The prosthetic partitioning device according to  claim 36 , wherein the actuator is pneumatic. 
     
     
         42 . The prosthetic partitioning device according to  claim 36 , further comprising one or more loops configured to secure the prosthetic partition device to the body conduit using one or more sutures, clips, and/or stents.