US2018134779A1PendingUtilityA1
Methods for treating diabetes
Est. expiryMay 6, 2018(expired)· nominal 20-yr term from priority
A61P 43/00C07K 16/18A61P 7/12C07K 2317/76A61K 38/1841A61K 38/18C07K 16/22A61P 3/10C07K 16/30A61K 2039/505A61P 5/50Y10S514/866
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Claims
Abstract
Methods for treating diabetes by administering an inhibitor of GDF-8, or a related member of Transforming Growth Factor-beta (TGF-β) superfamily of structurally-related growth factors (e.g., GDF-11) are disclosed. Also disclosed are methods for upregulating expression of hexose transporters, such as GLUT4 and GLUT 1, in a subject by administering an inhibitor of GDF-8. Also disclosed are methods for increasing glucose uptake by cells in a subject, by administering an inhibitor of GDF-8.
Claims
exact text as granted — not AI-modified1 - 11 . (canceled)
12 . A method of treating a subject suffering from a musculodegenerative disease, comprising administering to the subject an effective amount of a GDF-8 inhibitor, wherein the GDF-8 inhibitor is a receptor antibody.
13 . The method of claim 12 , wherein the musculodegenerative disease is sporadic inclusion body myositis.Join the waitlist — get patent alerts
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