Phenotypic Integrated Social Search Database and Method

Abstract

A method for generating correlations between human biological phenotype and human behavioral and/or emotional phenotype, and optionally to temporal location, comprising the steps of correlating data on biological phenotype with survey-based data on behavioral and/or emotional phenotype. The data on biological phenotype is collected from a sample from an individual, and the survey-based data can be collected from answers to behavioral and emotional questions from the individual or from observations of the individual by a third party. Correlations can further be used to predict behavior, including preferences, wellness needs and desires, and/or emotions. Feedback, advice and guidance can be provided to individuals based on such correlations. Such correlations are further useful for product and service providers and industries for purposes of standardizing or rating product quality and efficacy, and/or for promotion and selling purposes. A database comprising the data on biological phenotype and survey-based data is also provided.

1 .- 21 . (canceled) 
     
     
         22 . A database comprising information identifying a plurality of human subjects, data on biological phenotype of the plurality of subjects, survey-based data on behavioral and/or emotional phenotype of the plurality of subjects, and correlations between the data on biological phenotype from the plurality of subjects and the survey-based data on behavioral and/or emotional phenotype from the plurality of subjects,
 wherein the data on biological phenotype is collected from a plurality of samples from the plurality of subjects,   the survey-based data is collected from answers to social behavioral and emotional questions from the plurality of subjects or from observations of the plurality of subjects by a third party, and   the sample and the survey-based data are collected substantially simultaneously so that a temporal biologic condition or state can be correlated with a behavior and/or an emotion,   the database is configured to evolve when additional sample and survey-based data is added to the sample and survey-based data from the plurality of subjects by correlating the updated sample and survey-based data, and   wherein the data on biological phenotype includes data on a presence and/or a concentration of one or more polypeptides.   
     
     
         23 . The database of  claim 22 , wherein the data on biological phenotype further comprises data on presence or concentration of polynucleotides, metabolites, microbes, inorganic compounds, or ions in the sample. 
     
     
         24 . The database of  claim 22 , wherein the sample is a bodily fluid selected from the group consisting of blood, plasma, serum, bile, saliva, urine, tears, sweat, lacrimal fluid, mucus and nasal secretion, lymph, synovial fluid and cerebrospinal fluid. 
     
     
         25 . The database of  claim 22 , wherein the sample is selected from the group consisting of saliva, sweat, blood, tears, mucus, urine, stool, mouth cell scrapings, stool, breath, fart gas, hair follicle, fingernails, and other bodily cells. 
     
     
         26 . The database of  claim 22 , wherein the sample and the survey-based data, which are collected substantially simultaneously so that the temporal biologic condition or state is correlated with the behavior and/or the emotion, are also collected longitudinally for a same subject, so that more than one said temporal biologic condition or state is correlated with a behavior and/or an emotion of the same subject. 
     
     
         27 . The database of  claim 22 , further comprising the time that the sample is collected from the subject. 
     
     
         28 . The database of  claim 22 , wherein the sample tested for the presence or concentration of the polypeptide is a urine sample. 
     
     
         29 . (canceled) 
     
     
         30 . The database of  claim 22 , further comprising temporal location information of the plurality of subjects, and wherein the temporal location information is collected substantially simultaneously with the biological phenotype data or the survey-based data. 
     
     
         31 . (canceled) 
     
     
         32 . The database of  claim 22 , wherein the data has been collected passively, longitudinally, in real-time, using an undirected method, or using non-invasive methods. 
     
     
         33 . (canceled) 
     
     
         34 . The database of  claim 22 , wherein the behavior is lifestyle behavior, including one or more of preferences, wellness needs, deviations from wellness, personality traits and/or desires. 
     
     
         35 . (canceled) 
     
     
         36 . The database of  claim 22 , wherein the correlations are configured for use to provide feedback or guidance to the plurality of subjects, to provide information to a product provider or a service provider for use in marketing and/or selling of products and/or services, to provide a product provider or service provider with information useful in grading or rating products or services, or to provide a product provider or service provider with information useful to design new and/or better products or services. 
     
     
         37 . (canceled) 
     
     
         38 . The database of  claim 22 , wherein the human is a consumer. 
     
     
         39 . The database of  claim 22 , wherein the presence or concentration of the polypeptide in the sample is determined by using a biosensor. 
     
     
         40 . The database of  claim 22 , wherein the data on biological phenotype is selected from the group consisting of data on a presence and/or concentration of more than 10 of said polypeptides in a urine sample. 
     
     
         41 . The database of  claim 22 , wherein the database is configured to continue to accept new data selected from the group consisting of data on biological phenotype of the plurality of subjects, survey-based data on the behavioral and/or emotional phenotype, data on map locations, and data on environmental factors. 
     
     
         42 . The database of  claim 41 , wherein the database is configured to evolve to include at least one new correlation based on the new data. 
     
     
         43 . The database of  claim 22 , wherein the data on biological phenotype includes a ratio between concentrations of two biomarkers. 
     
     
         44 . The database of  claim 22 , wherein the data on biological phenotype includes a ratio between a concentration of a biomarker and a concentration of a housekeeping gene product. 
     
     
         45 . The database of  claim 22 , wherein the data on biological phenotype is selected from the group consisting of data on a presence and/or concentration of more than 100 of said polypeptides in the sample. 
     
     
         46 . The database of  claim 22 , wherein the data on biological phenotype further comprises data on a presence and/or concentration of more than 10 polynucleotides, metabolites, microbes, inorganic compounds and/or ions in the sample. 
     
     
         47 . A database comprising a subject, data on biological phenotype of the subject, survey-based data on behavioral and/or emotional phenotype of the subject, and correlations between human biological phenotype and human behavioral and/or emotional phenotype,
 the data on biological phenotype is collected from a sample from the subject,   the survey-based date is collected from answers to social behavioral and emotional questions from the subject or from observations of the subject by a third party,   the sample and the survey-based data are collected substantially simultaneously so that a temporal biologic condition or state can be correlated with a behavior and/or an emotion,   the database is configured to evolve when additional sample and survey-based data is added to the sample and survey-based data from the subject by correlating the updated sample and survey-based data, and   wherein the data on biological phenotype include data on presence and/or concentration of one or more polypeptides.   
     
     
         48 . The database of  claim 47 , wherein the database further comprises temporal location information of the subject, and wherein the temporal location information is collected substantially simultaneously with biological phenotype data or survey-based data. 
     
     
         49 . The database of  claim 47 , wherein the data has been collected passively, longitudinally, in real-time, using an undirected method, or using non-invasive methods. 
     
     
         50 . The database of  claim 47 , wherein the sample and the survey-based data, which are collected substantially simultaneously so that the temporal biologic condition or state is correlated with the behavior and/or the emotion, are also collected longitudinally from the subject, so that more than one said temporal biologic condition or state is correlated with the behavior and/or emotion of the subject. 
     
     
         51 . The database of  claim 47 , wherein the data on biological phenotype is selected from the group consisting of data on a presence and/or concentration of more than 10 polypeptides in a urine sample.