Glutamine & trehalose compositions

Abstract

Pharmaceutical compositions comprising glutamine and trehalose for treating side effects to oncology treatments are disclosed.

1 . A pharmaceutical composition comprising glutamine and trehalose and a pharmaceutically acceptable carrier. 
     
     
         2 . The pharmaceutical composition of  claim 1 , comprising 10-40% dry weight glutamine and 10-55% dry weight trehalose. 
     
     
         3 . The pharmaceutical composition of  claim 2 , formulated as a dried, free flowing powder. 
     
     
         4 . The pharmaceutical composition of  claim 1 , comprising a glutamine: trehalose ratio of 1:1 to 1:5. 
     
     
         5 . The pharmaceutical composition of  claim 4 , formulated as a dried, free flowing powder. 
     
     
         6 . The pharmaceutical composition of  claim 1 , reconstituted or formulated as a viscous fluid of at least 100 cP at 37° C. 
     
     
         7 . The pharmaceutical composition of  claim 1 , reconstituted or formulated as a viscous fluid of at least 1000 cP at 37° C. 
     
     
         8 . The pharmaceutical composition of  claim 1 , formulated as lozenge. 
     
     
         9 . The pharmaceutical composition of  claim 1 , formulated as a dissolvable gelatin or starch strip. 
     
     
         10 . The pharmaceutical composition of  claim 1 , further comprising sucrose. 
     
     
         11 . The pharmaceutical composition of  claim 1 , comprising 8% dry weight glutamine, 11% dry weight trehalose and 44% dry weight sucrose. 
     
     
         12 . The pharmaceutical composition of  claim 1 , comprising a dried powder having 8% glutamine, 11% trehalose and 44% sucrose. 
     
     
         13 . The pharmaceutical composition of  claim 1 , comprising a liquid having 8% dry weight glutamine, 11% dry weight trehalose and 44% dry weight sucrose, and flavorings and excipients.