US2018092916A1PendingUtilityA1

Methods of treating disease-induced ataxia and non-ataxic imbalance

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Individually held — no corporate assignee on recordPriority: Mar 31, 2008Filed: Oct 9, 2017Published: Apr 5, 2018
Est. expiryMar 31, 2028(~1.7 yrs left)· nominal 20-yr term from priority
Inventors:Theresa A. ZesiewiczKelly Sullivan
A61P 9/00A61P 9/02A61P 9/10A61P 43/00A61P 5/00A61P 27/02A61P 25/30A61P 25/16A61P 25/34A61P 25/08A61P 25/28A61P 25/32A61P 31/12A61P 25/00A61P 31/18A61P 31/00A61P 25/02A61P 3/00A61P 35/00A61P 25/18A61K 31/137A61K 31/435A61K 31/445A61K 31/4985A61K 31/465A61K 31/55A61K 31/4375A61K 31/498A61K 31/553A61K 45/06A61K 31/47A61K 31/138A61K 31/44A61P 21/00
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Claims

Abstract

Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic acetylcholine receptor activity.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating disease-induced ataxia or non-ataxic imbalance in a human, the method comprising administering to the human a compound having nicotinic acetylcholine receptor activity. 
     
     
         2 . The method of  claim 1  wherein the compound is selected from the group consisting of donepezil, exelon, fluoxetine, galantamine, huperzine A, MEM3454, MEM63908, tacrine, XY4083, and combinations thereof. 
     
     
         3 . The method of  claim 1  wherein the method is for treating ataxia resulting from a disease selected from Spinocerebellar ataxia, Friedriech's ataxia, and fragile X/tremor ataxia syndrome. 
     
     
         4 . The method of  claim 1  wherein the method is for treating non-ataxic imbalance resulting from a disease selected from Spinocerebellar ataxia, Friedriech's ataxia, and fragile X/tremor ataxia syndrome. 
     
     
         5 . The method of  claim 1  wherein the method is for treating ataxia resulting from Spinocerebellar ataxia or fragile X/tremor ataxia syndrome. 
     
     
         6 . The method of  claim 1  wherein the method is for treating non-ataxic imbalance resulting from Spinocerebellar ataxia or fragile X/tremor ataxia syndrome.

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