Separating agent for optical isomers

Abstract

Provided is a separating agent for optical isomers, which is excellent in solvent resistance and has optical separating ability comparable to or higher than that of existing separating agents for optical isomers of chemical bonding type or physical adsorption type. In the separating agent for optical isomers, amylose (3-chloro-5-methylphenylcarbamate) is supported on a carrier through chemical bonding.

What is claimed is: 
     
         1 . A separating agent for optical isomers, comprising amylose (3-chloro-5-methylphenylcarbamate) and a carrier wherein amylose (3-chloro-5-methylphenylcarbamate) is supported on the carrier through chemical bonding. 
     
     
         2 . The separating agent for optical isomers according to  claim 1 , wherein the separating agent for optical isomers is obtained by a method comprising a step of physically adsorbing amylose tris(3-chloro-5-methylphenylcarbamate) onto a carrier, and a step of crosslinking the amylose tris(3-chloro-5-methylphenylcarbamate) and the carrier through irradiation of light energy. 
     
     
         3 . The separating agent for optical isomers according to  claim 1 , wherein the separating agent for optical isomers is obtained by a method comprising a step of chemically bonding a reducing terminal of amylose and a carrier, and a step of, thereafter, causing hydroxyl groups of amylose and 3-chloro-5-methylphenylisocyanate to react. 
     
     
         4 . The separating agent for optical isomers according to  claim 1 , wherein the separating agent for optical isomers is obtained by a method comprising a step of copolymerizing a carrier having a polymerizable functional group, amylose (3-chloro-5-methylphenylcarbamate) having a polymerizable functional group, and a polymerizable monomer. 
     
     
         5 . The separating agent for optical isomers according to  claim 1 , wherein the separating agent for optical isomers is obtained by a method comprising a step of modifying hydroxyl groups of amylose with 3-chloro-5-methylphenylisocyanate, and thereafter obtaining an amylose derivative by modifying some of the remaining hydroxyl groups of the amylose with a compound represented by Formula (II), and a step of supporting the amylose derivative to be supported on a carrier through chemical bonding:
   A-X—Si(Y) n R 3-n    (II)
   wherein A represents a reactive group that reacts with hydroxyl groups or amino groups, X represents a branched or unbranched C1 to C18 alkylene group or an optionally substituted arylene group, Y represents a reactive group that reacts with a silanol group to form a siloxane bond, R represents a branched or unbranched C1 to C18 alkyl group or an optionally substituted aryl group, and n represents an integer ranging from 1 to 3.   
     
     
         6 . The separating agent for optical isomers according to  claim 1 , wherein the carrier is surface-treated silica gel.