Antifouling materials

Abstract

The invention provided herein presents a novel family of antifouling agents based on hydroxylated and fluorinated compounds.

1 . A compound comprising at least one 3,4-dihydroxy-L-phenylalanin (DOPA) group and at least one fluorinated carbon group. 
     
     
         2 . The compound according to  claim 1 , wherein said at least one fluorinated carbon group is a fluorinated alkyl group. 
     
     
         3 . The compound according to  claim 1 , wherein said at least one fluorinated carbon group is perfluorinated. 
     
     
         4 . The compound according to  claim 1 , having the general formula A-L-F, wherein A is DOPA, L is a covalent bond or a linker moiety linking A and F, and F is a fluorinated alkyl moiety. 
     
     
         5 . The compound according to  claim 4 , wherein the linker is selected from substituted or unsubstituted carbon chain, optionally comprising two or more amino acids. 
     
     
         6 . The compound according to  claim 5 , wherein the linker having the general structure 
       
         
           
           
               
               
           
         
         wherein 
         each * denotes a point of connectivity; 
         n is between 0 and 40; and 
         m is between 1 and 40. 
       
     
     
         7 . A method for preventing or arresting or minimizing or diminishing one or more of the following:
 (d) adsorption of organic and/or bio-organic materials to a surface;   (b) adsorption of proteins and/or (poly)saccharides and (poly)lipids to a surface;   (c) secretion from cells of multi-organism or of micro-organisms onto a surface; and   (d) adsorption of cells of multi-organism or micro-organisms to a surface,   the method comprising forming a coat of at least one compound according to  claim 1  on at least a region of said surface.   
     
     
         8 . A method for inhibiting settling, attachment, accumulation and dispersion of organisms, organism's secretion of an organic and/or bio-organic material on a surface, the method comprising contacting the surface with an effective amount of a formulation comprising a compound according to  claim 1 . 
     
     
         9 . A formulation comprising at least one compound according to  claim 1 . 
     
     
         10 . A film comprising at least one compound according to  claim 1 . 
     
     
         11 . An article or a device comprising at least one surface region coated with a film according to  claim 10 . 
     
     
         12 . A compound selected from 
       
         
           
           
               
               
           
         
       
     
     
         13 . A formulation comprising the compound: 
       
         
           
           
               
               
           
         
       
     
     
         14 . A biofouling film comprising the compound: