Anticariogenic agent and anticariogenic composition

Abstract

The present invention provides a novel anticariogenic agent without side effects so that anticariogenic effect can also be obtained in humans who are highly sensitive to oligosaccharides and sugar alcohols. Also, an agent for preventing periodontal disease or for treating periodontal disease which has an effect of preventing or treating periodontal disease and which does not have side effects is provided. The invention relates to an anticariogenic agent and an anticariogenic composition comprising a bifidobacterium, an agent and a composition for preventing periodontal disease comprising a bifidobacterium and an agent and a composition for treating periodontal disease comprising a bifidobacterium.

1 . An anticariogenic agent comprising a  bifidobacterium.    
     
     
         2 . The anticariogenic agent according to  claim 1 , wherein the  bifidobacterium  is  Bifidobacterium bifidum.    
     
     
         3 . The anticariogenic agent according to  claim 1 , wherein the  bifidobacterium  is  Bifidobacterium bifidum  OLB6378 strain (accession number: NITE BP-31). 
     
     
         4 . The anticariogenic agent according to  claim 1   3 , wherein the  bifidobacterium  is in the form of heat-treated cell. 
     
     
         5 . The anticariogenic agent according to  claim 1 , wherein the  bifidobacterium  is applied in an amount of 10 8  cells/day or more continuously for four weeks or longer. 
     
     
         6 . An anticariogenic composition comprising the anticariogenic agent according to  claim 1 . 
     
     
         7 . The anticariogenic composition according to  claim 6  further comprising a dispersant. 
     
     
         8 . The anticariogenic composition according to  claim 7 , wherein the dispersant is dextrin. 
     
     
         9 . A package comprising the anticariogenic composition according to  claim 6  and a packaging material, wherein the anticariogenic composition is packaged in the packaging material. 
     
     
         10 . An agent for preventing periodontal disease or an agent for treating periodontal disease, which comprises a  bifidobacterium.    
     
     
         11 . An anticariogenic agent, an agent for preventing periodontal disease or an agent for treating periodontal disease, which comprises a  bifidobacterium.    
     
     
         12 .  Bifidobacterium bifidum  OLB6378 strain (accession number: NITE BP-31) which has been heat treated.