US2018064675A1PendingUtilityA1

Active formulation for use in feed products

Assignee: PURAC BIOCHEM BVPriority: Jul 8, 2011Filed: Nov 13, 2017Published: Mar 8, 2018
Est. expiryJul 8, 2031(~4.9 yrs left)· nominal 20-yr term from priority
A61P 43/00A61P 31/04A61P 3/00A61P 1/00A23K 50/75A23K 20/24A23K 20/158A23K 20/105A61K 9/167A23K 40/10A61K 31/23A23K 20/10
43
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Claims

Abstract

Invention pertains to a free-flowing particulate powder including 2-90 wt. % of an active compound on a carrier, wherein the carrier has a D(v,0.1) of at least 100 microns, with the active compound being selected from lactylate in accordance with formula (1), Formula (1): R2-COO—[—CH(CH3)-COO]n-R1 or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof, a glycolylate of formula (2), Formula (2): R2-COO—[—CH2-COO]n-R1 or a Na, K, Ca, Mg, Fe(II), Zn, NH4, or Cu(II) salt thereof a lactate ester of formula (3), Formula (3): HO—CH(CH3)-COO—R2 and/or a glycolic acid ester of formula (4), Formula (4): HO—CH2-COO—R2 wherein in the above formulae R1 is selected from H, n stands for an integer with a value of 1-10, and R2 stands for a C1-C35 alkyl or alkenyl chain which may be branched or unbranched. The powder allows easy provision of the active compound to feed compositions.

Claims

exact text as granted — not AI-modified
1 . A free-flowing particulate powder comprising 10-90 wt. % of an active compound on a porous carrier, wherein the carrier has a D(v,0.1) of at least 100 microns, with the active compound being selected from lauroyl lactylate, myristoyl lactylate, their sodium salts, and mixtures thereof. 
     
     
         2 . The powder according to  claim 1 , wherein the powder has a Hausner ratio of at most 1.25. 
     
     
         3 . The powder according to  claim 1 , wherein the powder comprises at least 20 wt. % of the active compound. 
     
     
         4 . The powder according to  claim 1 , wherein the carrier has a surface area, as determined through BET, of at least 10 m 2 /g. 
     
     
         5 . The powder according to  claim 1 , wherein the carrier has a pore volume of at least 0.1 ml/g. 
     
     
         6 . The powder according to  claim 1 , wherein the carrier has a bulk density of at least 0.1 g/ml. 
     
     
         7 . The powder according to  claim 1 , wherein the carrier is a porous inorganic oxide. 
     
     
         8 . The powder according to  claim 1 , wherein the carrier is an organic porous material. 
     
     
         9 . The powder according to  claim 1 , wherein the active compound is a mixture comprising lauroyl lactylate and myristolyl lactylate, or the sodium salts of these compounds. 
     
     
         10 . The powder according to  claim 9 , wherein the mixture comprises 5-95 wt. % lauroyl lactylate, and 5-95 wt. % myristoyl lactylate, or the sodium salts of these compounds. 
     
     
         11 . The powder according to  claim 9 , wherein the mixture comprises 25-75 wt. % lauroyl lactylate, and 75-25 wt. % myristoyl lactylate, or the sodium salts of these compounds. 
     
     
         12 . A method for manufacturing a powder according to  claim 1 , comprising contacting the active compound in the liquid form with the carrier. 
     
     
         13 . The method for manufacturing a powder according to  claim 12 , wherein the contacting the active compound in the liquid form with the carrier is carried out at a pressure below 800 mbar. 
     
     
         14 . An animal nutrition composition comprising the powder according to  claim 1  and at least one further nutritious component. 
     
     
         15 . An animal nutrition composition comprising the powder according to  claim 1 . 
     
     
         16 . A method for preventing or treating intestinal infections caused by gram-positive bacteria in animals, and/or increasing the growth of the animal, comprising feeding the animal an effective amount of the powder of  claim 1 . 
     
     
         17 . The powder according to  claim 1 , wherein the carrier has a D(v,0.5) of between 300 and 800 microns.

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