US2018042944A1PendingUtilityA1

Pharmaceutical compositions

Assignee: GLAXOSMITHKLINE LLCPriority: Dec 14, 2012Filed: Oct 19, 2017Published: Feb 15, 2018

Est. expiryDec 14, 2032(~6.4 yrs left)· nominal 20-yr term from priority

Inventors:Shenshen Cai Brian Alvin Johns Andrew Spaltenstein

A61P 43/00A61P 31/18C07J 63/008A61K 31/575A61K 31/568A61K 45/06

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Claims

Abstract

The present Invention relates to long acting pharmaceutical compositions of betulin derivatives or pharmaceutically acceptable salts thereof, useful in the treatment or prevention of Human Immunodeficiency Virus (HIV) infections.

Claims

exact text as granted — not AI-modified

1 . A method for the treatment of an HIV infection in a human having an HIV infection, comprising: administering to the human a LAP pharmaceutical composition including the compound of Formula I 
       
         
           
           
               
               
           
         
         or a pharmaceutically acceptable salt thereof, 
         in combination with one or more additional compounds selected from the group consisting of dolutegravir, ritonavir, rilpivirine, and a compound having the following structure:

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