Sensors for continuous analyte monitoring, and related methods

Abstract

Sensor devices including dissolvable tissue-piercing tips are provided. The sensor devices can be used in conjunction with dissolvable needles configured for inserting the sensor devices into a host. Hardening agents for strengthening membranes on sensor devices are also provided. Methods of using and fabricating sensor devices are also provided.

What is claimed is: 
     
         1 . A method of making a sensor device configured for implantation in a host without use of an inserter, the method comprising:
 forming a piercing tip on a sensor unit, the sensor unit including a sensor body, at least one electrode, and a membrane covering at least a portion of the at least one electrode;   wherein the membrane is applied to the sensor unit prior to forming the piercing tip on the sensor unit.   
     
     
         2 . The method of  claim 1 , further comprising applying the membrane to the sensor unit. 
     
     
         3 . The method of  claim 1 , wherein forming the piercing tip comprises forming an annular channel about a circumference of a wire that is coated with the membrane. 
     
     
         4 . The method of  claim 3 , wherein the annular channel extends through the membrane and partially into the wire. 
     
     
         5 . The method of  claim 3 , further comprising applying tension to the coated wire. 
     
     
         6 . The method of  claim 5 , wherein the tension induces strain in the wire proximate the annular channel, causing the wire to neck and fracture. 
     
     
         7 . The method of  claim 6 , wherein the necking forms the piercing tip on the sensor body. 
     
     
         8 . The method of  claim 7 , further comprising covering the piercing tip with a protective outer layer.