US2017369467A1PendingUtilityA1

Process for the Preparation of N-Monosubstituted beta-Amino Alcohols

Assignee: LONZA AGPriority: Jul 9, 2002Filed: Sep 8, 2017Published: Dec 28, 2017
Est. expiryJul 9, 2022(expired)· nominal 20-yr term from priority
C07D 307/46C07D 333/20C07D 333/22C07D 333/56C07C 213/00C07D 333/16C07C 225/16C07D 307/52C07D 307/42C07C 221/00C07D 307/80C07C 215/08C07C 213/08
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Claims

Abstract

A process is disclosed for the preparation of a compound of formula and/or an addition salt of a proton acid, wherein R 1 and R 2 independently represent alkyl, cycloalkyl, aryl or aralkyl, each aryl or aralkyl being optionally further substituted with alkyl, alkoxy and/or halogen.

Claims

exact text as granted — not AI-modified
1 .- 20 . (canceled) 
     
     
         21 . A process for preparing (S)-(+)-N-methyl-[3-(1-naphthyloxy)-3-(2-thienyl)-propyl]-amine comprising converting a compound of formula I 
       
         
           
           
               
               
           
         
       
       to (S)-(+)-N-methyl-[3-(1-naphthyloxy)-3-(2-thienyl)-propyl]-amine, wherein R 1  is thienyl and R 2  is methyl. 
     
     
         22 . The process of  claim 21 , wherein the compound of formula I is (S)-(−)-3-N-methylamino-1-(2-thienyl)-1-propanol.

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