US2017368030A1PendingUtilityA1

Dihydropyrazoles

57
Assignee: MERCK PATENT GMBHPriority: Jul 1, 2011Filed: Aug 23, 2017Published: Dec 28, 2017
Est. expiryJul 1, 2031(~4.9 yrs left)· nominal 20-yr term from priority
Inventors:Henry YuThomas E. RichardsonRobert James FoglesongLizbeth Celeste DeselmAndreas Goutopoulos
A61P 5/06A61P 43/00A61P 15/08A61K 31/4155C07D 471/04A61K 9/0019A61K 9/0048C07D 405/06C07D 401/06C07D 231/06A61K 31/437C07D 413/06A61K 9/48C07D 405/04C07D 405/14A61K 31/506C07D 405/10C07D 405/12C07D 417/10A61K 9/06C07D 413/10A61K 47/06C07D 409/04A61K 9/2018C07D 403/04A61K 9/0031C07D 413/04A61K 9/2059C07D 401/10A61K 31/415A61K 31/427A61K 9/0014C07D 401/04A61K 9/19C07D 403/06A61K 9/0078C07D 409/06A61K 45/06C07D 231/12C07D 403/10A61K 31/423A61K 31/5377C07D 231/08C07D 401/14A61K 31/4709
57
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Claims

Abstract

Novel dihydropyrazole derivatives of formula (I) wherein L, R, R 3 , R 4 , R 5 , R 6 , R 7 , X 1 , X 2 , X 3 , X 4 , Y, m and n have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.

Claims

exact text as granted — not AI-modified
1 - 14 . (canceled) 
     
     
         15 . A compound selected from:

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