US2017347661A1PendingUtilityA1

Composition comprising antimicrobial metal ions and a quaternary cationic surfactant

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Assignee: CONVATEC TECHNOLOGIES INCPriority: Apr 6, 2011Filed: Jun 12, 2017Published: Dec 7, 2017
Est. expiryApr 6, 2031(~4.7 yrs left)· nominal 20-yr term from priority
Inventors:David Parsons
A61P 31/04A61P 31/00A61P 17/02A61K 9/0014A61K 33/30A61K 33/245A61K 31/198A61K 33/32A61K 9/06A61K 33/26A61K 31/14A61K 33/34A61K 33/38A01N 33/12A01N 37/44A01N 59/20A01N 59/16A61K 33/24
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Claims

Abstract

The present invention relates to an antimicrobial composition suitable for use on skin and wounds comprising a source of an antimicrobial metal ion and a quaternary cationic surfactant.

Claims

exact text as granted — not AI-modified
1 . An antimicrobial composition comprising ionic silver, EDTA, and a quaternary cationic surfactant, wherein the quaternary cationic surfactant is present at a level of more than or equal to 0.025% by weight. 
     
     
         2 . A composition as claimed in  claim 1  having a pH from 4 to 8. 
     
     
         3 . (canceled) 
     
     
         4 . (canceled) 
     
     
         5 . A composition as claimed in  claim 1 , wherein the ionic silver is included in the composition at a level of from 0.01% to 10% by weight. 
     
     
         6 . A composition as claimed in  claim 1 , wherein the composition is in aqueous solution, and the ionic silver is present at a level of from 0.00001% to 1.0% by weight of the composition. 
     
     
         7 . (canceled) 
     
     
         8 . A composition as claimed  claim 1 , wherein the cationic surfactant is selected from the group of the salts where the cation is benzethonium, benzalkonium, dimethyldiakylonium, alkylpyridinium and alkyltrimethylammonium. 
     
     
         9 . A composition as claimed in  claim 1 , wherein the quaternary cationic surfactant is present at a level of from 0.05% to 4% by weight. 
     
     
         10 . A composition as claimed in  claim 1 , wherein the EDTA is present as the di-, tri- or tetra-basic salt of EDTA. 
     
     
         11 . A composition as claimed in  claim 1 , wherein the EDTA is present in the composition at a level of 0.1% to 4% by weight of the composition. 
     
     
         12 . A process for making an antimicrobial wound dressing comprising:
 (i) obtaining an absorbent wound dressing, and   (ii) treating the dressing with a composition as claimed in  claim 1 .   
     
     
         13 . (canceled) 
     
     
         14 . A composition as claimed in  claim 1 , wherein the quaternary cationic surfactant is selected from benzethonium chloride and benzalkonium chloride. 
     
     
         15 . A composition as claimed in  claim 1  having a pH from 4.5 to 5.5. 
     
     
         16 . A composition as claimed in  claim 1 , wherein the quaternary cationic surfactant is present at a level of from 0.5% to 2% by weight. 
     
     
         17 . A composition as claimed in  claim 1 , wherein the EDTA is present in the composition at a level of 0.2% to 1% by weight.

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