Peptides for targeting gastric cancer, and medical use tehreof

Abstract

Provided is a peptide for targeting gastric cancer, a composition for diagnosing radioresponsiveness-dependent gastric cancer using the peptide, and a drug delivery use of the peptide, wherein a functional peptide capable of targeting cancer has been discovered so as to implement personalized diagnosis and treatment for individual patients having cancer, consideration of problems occurring during treatment in which treatment cases of respective patients differ due to different therapeutic responses resulting from genetic differences in the individual patients.

1 . A peptide for targeting gastric cancer, the peptide comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1 to 6. 
     
     
         2 . The peptide of  claim 1 , wherein the peptide comprising an amino acid selected from the group consisting of SEQ ID NOs: 1 to 3 is specific to an irradiated gastric cancer tissue. 
     
     
         3 . A polynucleotide encoding the peptide of  claim 1 . 
     
     
         4 . A method for diagnosing gastric cancer, comprising:
 obtaining a gastric cancer tissue sample from a patient;   transplanting the tissue sample into a subject;   applying the composition comprising the peptide of  claim 1  to the subject; and   identifying the presence of the gastric cancer.   
     
     
         5 . A method for diagnosing radio-sensitive gastric cancer, comprising:
 obtaining a gastric cancer tissue sample from a patient;   transplanting the tissue sample into a subject;   applying the composition comprising the peptide of claim of  2  to the subject; and   identifying the presence of the radio-sensitive gastric cancer.   
     
     
         6 . The method of  claim 4 , wherein the peptide is labeled with one selected from the group consisting of a chromogenic enzyme, a radioactive isotope, a chromopore, and a luminescent or fluorescent material. 
     
     
         7 . A composition for delivering a drug, the composition comprising the peptide of  claim 1 . 
     
     
         8 . The composition of  claim 7 , wherein the drug comprises an anticancer drug.