Use of one or a combination of phyto-cannabinoids in the treatment of epilepsy

Abstract

This invention relates to the use of one or more cannabinoids in the treatment of epilepsy and more particularly to the use of one or a combination of cannabinoids in the treatment of generalized or partial seizure. In one embodiment it relates to the use of the cannabinoid THCV, as a pure or isolated compound, or as a plant extract in which significant amounts of any THC naturally present has been selectively removed. In another embodiment the phytocannabinoid is CBD.

1 .- 10 . (canceled) 
     
     
         11 . A method of treating complex partial seizure that remains localized comprising administering cannabidiol (CBD) to a patient wherein the CBD is present in an amount which provides a daily dose of at least 400 mg. 
     
     
         12 . The method of  claim 11 , wherein CBD is present in an amount which provides a daily dose of from 400 to 800 mg. 
     
     
         13 . The method of  claim 11 , wherein the CBD is used in combination with tetrahydrocannabivarin (THCV). 
     
     
         14 . The method of  claim 13 , wherein the THCV is present in an amount which provides a daily dose of at least 1.5 mg. 
     
     
         15 . he method of  claim 14 , wherein the THCV is present in an amount which provides a daily dose of at least 15 mg. 
     
     
         16 . The method of  claim 11 , wherein the CBD is present as a plant extract. 
     
     
         17 . The method of  claim 16 , wherein the plant extract comprises less than 5% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract. 
     
     
         18 . The method of  claim 17 , wherein the plant extract comprises less than 1% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract. 
     
     
         19 . The method of  claim 11 , wherein the CBD is present as a pure or isolated cannabinoid. 
     
     
         20 . The method of  claim 13 , wherein the CBD in combination with THCV is present as a plant extract. 
     
     
         21 . The method of  claim 20 , wherein the plant extract comprises less than 5% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract. 
     
     
         22 . The method of  claim 21 , wherein the plant extract comprises less than 1% by weight of tetrahydrocannabinol (THC) as a percentage of any cannabinoids present in the plant extract. 
     
     
         23 . The method of  claim 13 , wherein the CBD in combination with THCV is present as a pure or isolated cannabinoid.