US2017239265A1PendingUtilityA1

Drug for preventing and/or treating polycystic kidney disease

Assignee: OTSUKA PHARMA CO LTDPriority: May 31, 2012Filed: May 5, 2017Published: Aug 24, 2017
Est. expiryMay 31, 2032(~5.9 yrs left)· nominal 20-yr term from priority
A61P 43/00A61P 13/12A61P 13/00A61K 31/55A61K 45/06A61K 38/31A61K 9/0053A61K 9/0019A61K 38/10
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Claims

Abstract

An object of the present invention is to provide a combination drug that has remarkably excellent preventive and/or therapeutic effects on polycystic kidney disease. The present invention provides a drug for preventing and/or treating polycystic kidney disease comprising a combination of tolvaptan or a prodrug thereof with a somatostatin derivative, and a method for treating polycystic kidney disease using this drug.

Claims

exact text as granted — not AI-modified
1 - 3 . (canceled) 
     
     
         4 . A method for treating polycystic kidney disease, comprising administering tolvaptan or a prodrug thereof in combination with at least one member selected from the group consisting of pasireotide, lanreotide, vapreotide and a salt thereof to a polycystic kidney disease patient. 
     
     
         5 . The method according to  claim 4 , wherein the tolvaptan or prodrug thereof is orally administered, and said at least one member selected from the group consisting of pasireotide, lanreotide, vapreotide and a salt thereof is subcutaneously or intramuscularly administered to the polycystic kidney disease patient. 
     
     
         6 . The method according to  claim 4 , wherein the dose of tolvaptan or a prodrug thereof is less than an effective dose when used alone. 
     
     
         7 . The method according to  claim 5 , wherein the dose of tolvaptan or a prodrug thereof is less than an effective dose when used alone.

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