US2017226064A1PendingUtilityA1

Synthesis of Triethylenetetramines

Assignee: PHILERA NEW ZEALAND LTDPriority: Jul 19, 2004Filed: May 3, 2017Published: Aug 10, 2017
Est. expiryJul 19, 2024(expired)· nominal 20-yr term from priority
A61P 7/00A61P 39/04A61P 3/10A61P 1/16C07C 57/15C07C 55/10C07C 255/30C07C 211/10C07D 233/26C07B 2200/13C07D 233/02C07C 211/14C07C 209/76C07C 209/48C07C 209/62C07C 57/145C07C 211/13
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Claims

Abstract

Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.

Claims

exact text as granted — not AI-modified
1 . A compound of formula (II), 
       
         
           
           
               
               
           
         
         wherein each R of formula (II) is independently methyl carbamate, ethyl carbamate, benzyl carbamate, tert-butyl carbamate, tert-butyloxycarbonyl (Boc), cyclohexanone, 2,2,6,6-tetramethyl cyclohexanone, anthrone, an alkyl group, an aryl group, or an aromatic alkyl group, 
       
       or a compound of formula (VI), 
       
         
           
           
               
               
           
         
         wherein each R of formula (VI) is independently methyl carbamate, ethyl carbamate, benzyl carbamate, tert-butyl carbamate, tert-butyloxycarbonyl (Boc), cyclohexanone, 2,2,6,6-tetramethyl cyclohexanone, anthrone, an alkyl group, an aryl group, or an aromatic alkyl group. 
       
     
     
         2 . The compound of  claim 1 , wherein R is tert-butyloxycarbonyl (Boc). 
     
     
         3 . The compound of  claim 1 , wherein the compound is crystallized. 
     
     
         4 . The compound of  claim 1 , wherein the compound is substantially pure. 
     
     
         5 . The compound of  claim 3 , wherein the compound is substantially pure.

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