Method and Apparatus for Determining Meal Start and Peak Events in Analyte Monitoring Systems

Abstract

Systems, methods and apparatus are provided for estimating meal start and peak meal response times are provided based on time series of sampled glucose data collected. Numerous additional aspects are disclosed.

What is claimed is: 
     
         1 . A method, comprising:
 determining time derivatives of a plurality of data points corresponding to monitored analyte level;   determining an optima of acceleration of the plurality of data points based on the determined time derivatives;   removing false carbohydrate intake start and peak carbohydrate intake response pairs having an amplitude below a predetermined level;   removing carbohydrate intake start candidate from the most recent last carbohydrate intake peak response candidate based on one or more of a proximity or level drop of the carbohydrate intake start candidate from the most recent last carbohydrate intake peak response candidate;   removing one or more unpaired carbohydrate intake start candidates;   removing one or more signal artifacts falsely identified as carbohydrate intake start and carbohydrate intake peak response pair; and   identifying carbohydrate intake start and carbohydrate intake peak response pairs of the plurality of data points corresponding to the monitored analyte level.   
     
     
         2 . The method of  claim 1 , further including conditioning the plurality of data points corresponding to the monitored analyte level over a first time period. 
     
     
         3 . The method of  claim 2 , wherein performing conditioning on the plurality of data points corresponding to the monitored analyte level of the first time period includes:
 performing sample data analysis on the plurality of data points to remove questionable data; and   smoothing the plurality of data points.   
     
     
         4 . The method of  claim 2 , wherein the time derivatives of the plurality of data points are determined based on the conditioned plurality of data points. 
     
     
         5 . The method of  claim 1 , wherein determining the optima of acceleration of the plurality of data points based on the determined time derivatives includes determining acceleration of the plurality of data points based on the determined time derivatives. 
     
     
         6 . The method of  claim 1 , further including outputting an indication associated with a carbohydrate intake start event. 
     
     
         7 . The method of  claim 6 , wherein the carbohydrate intake start event includes a meal start event. 
     
     
         8 . The method of  claim 1 , further including outputting an indication associated with a peak carbohydrate intake response event. 
     
     
         9 . The method of  claim 8 , wherein the peak carbohydrate intake response event includes a peak meal response event. 
     
     
         10 . The method of  claim 1 , further including refining the identified carbohydrate intake start and peak carbohydrate intake response pairs. 
     
     
         11 . An apparatus, comprising:
 a user interface component; and   one or more processors operatively coupled to the user interface component, the one or more processors configured to determine time derivatives of a plurality of data points corresponding to monitored analyte level, an optima of acceleration of the plurality of data points based on the determined time derivatives, remove false carbohydrate intake start and peak carbohydrate intake response pairs having an amplitude below a predetermined level, remove carbohydrate intake start candidate from the most recent last carbohydrate intake peak response candidate based on one or more of a proximity or level drop of the carbohydrate intake start candidate from the most recent last carbohydrate intake peak response candidate, remove one or more unpaired carbohydrate intake start candidates, remove one or more signal artifacts falsely identified as carbohydrate intake start and carbohydrate intake peak response pair, identify carbohydrate intake start and carbohydrate intake peak response pairs of the plurality of data points corresponding to the monitored analyte level.   
     
     
         12 . The apparatus of  claim 11 , wherein the one or more processors is further configured to condition the plurality of data points corresponding to the monitored analyte level over a first time period. 
     
     
         13 . The apparatus of  claim 12 , wherein the one or more processors configured to condition the plurality of data points corresponding to the monitored analyte level over the first time period includes the one or more processors configured to perform sample data analysis on the plurality of data points to remove questionable data, and to smooth the plurality of data points. 
     
     
         14 . The apparatus of  claim 12 , wherein the time derivatives of the plurality of data points are determined based on the conditioned plurality of data points. 
     
     
         15 . The apparatus of  claim 11 , wherein the one or more processors configured to determine the optima of acceleration of the plurality of data points based on the determined time derivatives includes the one or more processors configured to determine acceleration of the plurality of data points based on the determined time derivatives. 
     
     
         16 . The apparatus of  claim 11 , wherein the one or more processors is further configured to output an indication associated with a carbohydrate intake start event on the user interface component. 
     
     
         17 . The apparatus of  claim 16 , wherein the carbohydrate intake start event includes a meal start event. 
     
     
         18 . The apparatus of  claim 11 , wherein the one or more processors is further configured to output an indication associated with a peak carbohydrate intake response event on the user interface component. 
     
     
         19 . The apparatus of  claim 18 , wherein the peak carbohydrate intake response event includes a peak meal response event. 
     
     
         20 . The apparatus of  claim 11 , wherein the one or more processors is further configured to refine the identified carbohydrate intake start and peak carbohydrate intake response pairs.