US2017172964A1PendingUtilityA1
Composition for Treatment of Skin
Est. expiryFeb 6, 2029(~2.5 yrs left)· nominal 20-yr term from priority
Inventors:Keith Coupland
A61P 43/00A61K 8/922A61K 36/30A61K 31/202A61Q 19/08A61K 31/232A61K 47/543A61K 8/361A61K 8/37A61K 9/0014A61P 17/00A61K 47/48046
45
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Claims
Abstract
The present invention provides a composition comprising stearidonic acid (or an ester thereof) derived for example from Echium oil, and an additional lipid (derived for example from calendula oil) which enhances the pro-collagen effects of stearidonic acid. The composition is useful in reducing visible signs of aging of human or animal skin or a method of wound healing.
Claims
exact text as granted — not AI-modified1 .- 15 . (canceled)
16 . A composition for topical application to the human or animal body comprising stearidonic acid which is provided by oil extracted from the seeds of the Boraginacae family, or an ester thereof, and an additional lipid which is a conjugated octadecatrienoic acid or an ester thereof which enhances the pro-collagen effects of stearidonic acid.
17 . A composition as claimed in claim 16 , wherein said additional lipid is calendic acid, catalpic acid, α-eleostearic acid, jacaric acid, punicic acid, esters of any of the foregoing acids, or any combination of the foregoing.
18 . A composition as claimed in claim 17 , wherein said acids are extracted from Calendula officinalis, Catalpa ovata, Aleurites fordii, Jacaranda mimosifolia and Punica granatum respectively.
19 . A composition as claimed in claim 16 , wherein the amount of said oil is from 0.1% to 10% w/w.
20 . A composition as claimed in claim 16 , additionally comprising a physiologically acceptable carrier.
21 . A composition as claimed in claim 16 , wherein the amount of said additional lipid is from 0.005 to 1% w/w.
22 . A composition as claimed in claim 16 for use in a method of therapy practiced on the human or animal body.
23 . A composition as claimed in claim 16 for use in a method of reducing visible signs of aging of human or animal skin.
24 . A composition as claimed in claim 16 for use in a method of wound healing.
25 . A method of reducing visible signs of aging of human or animal skin comprising applying to said skin either a composition comprising Echium oil or a composition as claimed in claim 16 in combination with a physiologically acceptable carrier.
26 . A method of healing wounds in a human or animal body comprising applying to the locus of the wound either a composition comprising Echium oil or a composition as claimed in claim 16 in combination with a physiologically acceptable carrier.
27 . A method of reducing trans-epidermal water loss comprising applying to the locus of the wound either a composition comprising Echium oil or a composition as claimed in claim 16 in combination with a physiologically acceptable carrier.
28 . A composition comprising Echium oil or calendula oil or a mixture thereof for use in the stimulation of collagen synthesis in skin cells.
29 . A composition comprising Echium oil for use in the reduction of trans-epidermal water loss.
30 . A composition comprising Echium oil for use in the reduction of skin wrinkles.Join the waitlist — get patent alerts
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