US2017151289A1PendingUtilityA1

Formulations and methods for treatment of wounds and inflammatory skin conditions

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Assignee: ZEMTSOV ENTPR LLCPriority: Apr 16, 2012Filed: Feb 13, 2017Published: Jun 1, 2017
Est. expiryApr 16, 2032(~5.7 yrs left)· nominal 20-yr term from priority
Inventors:Alexander Zemtsov
A61K 47/44A61K 31/495A61K 31/201A61K 47/14A61K 31/20A61K 31/573A61K 31/57A61K 31/203A61K 9/0014A61P 17/00A61K 31/197A61K 35/57A61K 45/06A61K 9/06A61K 31/202A61K 47/10A61P 17/06A61P 17/08A61K 31/4168A61P 17/02A61P 17/10
58
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Claims

Abstract

The disclosure of the present application includes topically administrable compositions and methods for treating wounds and inflammatory conditions of the skin in mammals. In an exemplary embodiment, the composition includes a therapeutic amount of antihistamine selected from the group consisting of a non-sedating antihistamine, a physiologically acceptable acid of a non-sedating antihistamine, a salt of a non-sedating antihistamine, an amide of a non-sedating antihistamine, and a combination of two or more of these; a therapeutic amount of creatine; a therapeutic amount of creatinine; and emu oil product selected from the group consisting of emu oil, a biologically active fraction of emu oil, and a combination of these. The combination of non-sedating antihistamine, creatine, and creatinine with emu oil has been found to produce a synergistic effect that is more effective in the treatment of skin wounds than the compounds used separately.

Claims

exact text as granted — not AI-modified
1 . A composition, comprising:
 a quantity of a non-sedating antihistamine;   a quantity of creatine;   a quantity of creatinine; and   a quantity of an emu oil product.   
     
     
         2 . The composition of  claim 1 , wherein:
 the quantity of the non-sedating antihistamine comprises 0.1-5.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         3 . The composition of  claim 1 , wherein:
 the quantity of the non-sedating antihistamine comprises 0.1-5.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 85% by weight.   
     
     
         4 . The composition of  claim 1 , wherein:
 the quantity of the non-sedating antihistamine comprises 1.0-3.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         5 . The composition of  claim 1 , wherein the non-sedating antihistamine comprises cetirizine. 
     
     
         6 . The composition of  claim 5 , wherein:
 the quantity of the cetirizine comprises 0.1-5.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         7 . The composition of  claim 5 , wherein:
 the quantity of the cetirizine comprises 0.1-5.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 85% by weight.   
     
     
         8 . The composition of  claim 5 , wherein:
 the quantity of the cetirizine comprises 1.0-3.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         9 . The composition of  claim 5 , wherein:
 the quantity of the cetirizine comprises 1.0-3.0% by weight; and   the quantity of the creatine and the quantity of the creatinine comprises 1.0-2.0% by weight in combination.   
     
     
         10 . The composition of  claim 1 , wherein the non-sedating antihistamine comprises levocetirizine. 
     
     
         11 . The composition of  claim 10 , wherein:
 the quantity of the levocetirizine comprises 0.1-5.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         12 . The composition of  claim 10 , wherein:
 the quantity of the levocetirizine comprises 0.1-5.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 85% by weight.   
     
     
         13 . The composition of  claim 10 , wherein:
 the quantity of the levocetirizine comprises 1.0-3.0% by weight;   the quantity of the creatine comprises 0.2-10.0% by weight;   the quantity of the creatinine comprises 0.1-5.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         14 . The composition of  claim 10 , wherein:
 the quantity of the cetirizine comprises 1.0-3.0% by weight; and   the quantity of the creatine and the quantity of the creatinine comprises 1.0-2.0% by weight in combination.   
     
     
         15 . A composition, comprising:
 a quantity of a non-sedating antihistamine or an acid, salt, or amide thereof;   a quantity of a mixture comprising creatine and creatinine; and   a quantity of an emu oil product;   wherein the quantity of the mixture comprising creatine and creatinine is 0.2-10% by weight.   
     
     
         16 . The composition of  claim 15 , wherein:
 the non-sedating antihistamine comprises cetirizine or levocetirizine; and   wherein the quantity of the mixture comprising creatine and creatinine is 1.0-2.0% by weight.   
     
     
         17 . The composition of  claim 16 , wherein:
 the quantity of the non-sedating antihistamine comprises 1.0-3.0% by weight; and   the quantity of the emu oil product is at least 75% by weight.   
     
     
         18 . The composition of  claim 17 , further comprising:
 a quantity of a preservative.   
     
     
         19 . A composition, comprising:
 a quantity of cetirizine or levocetirizine;   a quantity of a mixture comprising creatine and creatinine; and   a quantity of an emu oil product of at least 75% by weight.   
     
     
         20 . The composition of  claim 19 , wherein:
 the quantity of the mixture comprising creatine and creatinine is 1.0-2.0% by weight.

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