Pharmaceutical salts

Abstract

The invention relates to pharmaceutical salts comprised of a pharmaceutical active substance and of at least one sugar substitute, to medicaments containing these salts, and to the use of these salts for producing medicaments.

1 . A pharmaceutical salt of a salt-forming pharmaceutical active compound and at least one salt-forming sugar substitute, wherein the salt-forming pharmaceutical active compound is a salt-forming 1-phenyl-3-dimethylaminopropane compound selected from the group consisting of: (a) (−)-(1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol; (b) (1RS,3RS,6RS)-6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol; and (c) (−)-(1R,2R)-3-(2-Dimethylaminomethyl-cyclohexyl)-phenol. 
     
     
         2 . The pharmaceutical salt according to  claim 1 , wherein the salt-forming pharmaceutical active compound is (−)-(1R,2R)-3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)-phenol. 
     
     
         3 . The pharmaceutical salt according to  claim 1 , wherein the salt-forming pharmaceutical active compound is (1RS,3RS,6RS)-6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol. 
     
     
         4 . The pharmaceutical salt according to  claim 1 , wherein the salt-forming pharmaceutical active compound is (−)-(1R,2R)-3-(2-Dimethylaminomethyl-cyclohexyl)-phenol. 
     
     
         5 . A pharmaceutical composition comprising a therapeutically effective amount of the pharmaceutical salt according to  claim 1  and optionally one or more physiologically tolerable excipients. 
     
     
         6 . A method of controlling pain comprising administering to a patient in need thereof a pain-controlling effective amount of the pharmaceutical salt of  claim 1 . 
     
     
         7 . A method of controlling urinary incontinence comprising administering to a patient in need thereof an urinary incontinence-controlling effective amount of the pharmaceutical salt of  claim 1 .