Neuroendocrine Tumor Treatment

Abstract

A method for treating endocrine tumors by administration of an mTOR inhibitor, optionally in combination with another drug.

1 . A method for treating endocrine tumors, comprising administering to a subject in need thereof a therapeutically effective amount of an mTOR inhibitor. 
     
     
         2 . A method for inhibiting growth of endocrine tumors, comprising administering to a subject in need thereof a therapeutical effective amount of an mTOR inhibitor. 
     
     
         3 . A method for inhibiting or controlling endocrine tumors, comprising administering to a subject in need thereof a therapeutically effective amount of an mTOR inhibitor. 
     
     
         4 . A method for inducing endocrine tumor regression, comprising administering to a subject in need thereof a therapeutically effective amount of an mTOR inhibitor. 
     
     
         5 . A method for treating endocrine tumor invasiveness or symptoms associated with such tumor growth, comprising administering to a subject in need thereof a therapeutically effective amount of an mTOR inhibitor. 
     
     
         6 . A method for preventing metastatic spread of endocrine tumors or for preventing or inhibiting growth of micrometastasis, comprising administering to a subject in need thereof a therapeutically effective amount of an mTOR inhibitor. 
     
     
         7 . A method for the treatment of a disorder associated with endocrine tumors, comprising administering to a subject in need thereof a therapeutically effective amount of an mTOR inhibitor. 
     
     
         8 . A method according to  claim 1 , comprising administering in addition a therapeutically effective amount of at least one second drug substance. 
     
     
         9 . A method according to  claim 8 , wherein a second drug substance is somastatin or a somastatin analogue. 
     
     
         10 . The use of an mTOR inhibitor for the manufacture of a medicament for use in a method according to  claim 1 . 
     
     
         11 . A method according to  claim 1 , or the use according to  claim 10 , wherein an mTOR inhibitor is selected from rapamycin or a rapamycin derivative. 
     
     
         12 . A method according to  claim 10 , wherein an mTOR inhibitor is 40-O-(2-hydroxyethyl)-rapamycin.