Cardiac cell culture material

Abstract

The purpose of the present invention is to provide a cardiac cell culture material which specifically acts on cardiac cells. In addition, another purpose of the present invention is to provide artificial organ material obtained by culturing by using said cardiac cell culture material, and a method for producing the same. Thus, provided is a cardiac cell culture, wherein functional cardiac tissue is favorably built by using a cardiac cell culture material containing VCAM-1.

1 . A cardiac cell culture material comprising a fibroblast expressing VCAM-1 protein. 
     
     
         2 . The cardiac culture material according to  claim 1  used for culturing to construct a cardiac tissue. 
     
     
         3 . The cardiac cell culture material according to  claim 1 , wherein the fibroblast is a cardiac-derived fibroblast. 
     
     
         4 . The cardiac cell culture material according to  claim 1 , wherein the fibroblast is an epicardial-derived cell-derived fibroblast. 
     
     
         5 . A cell culture substrate, wherein a wall surface and/or a bottom surface of the culture substrate having the wall surface and/or the bottom surface are coated with the cardiac cell culture material according to  claim 1 . 
     
     
         6 . An artificial organ material obtained by co-culturing a cardiac cell with the cardiac cell culture material according to  claim 1 . 
     
     
         7 . A method of producing an artificial organ material comprising a step of co-culturing a cardiac cell with the cardiac cell culture material according to  claim 1 . 
     
     
         8 . A method for curing heart diseases by attaching a sheet to a damaged part of the heart wherein, the sheet is constructed from the cardiac cell culture material according to  claim 1 . 
     
     
         9 . A method for constructing a functional cardiac tissue by attaching a sheet to a damaged part of the heart wherein, the sheet is constructed from the cardiac cell culture material according to  claim 1 .