Flash chromatography cartridge

Abstract

A low pressure liquid chromatographic cartridge has a tubular polymer container that receives a chromatographic packing material. The container has an outlet port located at its downstream end and container threads formed on its upstream end. A polymer cap, with an inlet port on an upstream end, screws onto the container threads. A flange depending from the cap mates with the lip of the container to form a fluid tight seal between the polymer cap and container suitable for use in low pressure liquid chromatography.

1 . A low pressure liquid chromatographic cartridge, comprising:
 a tubular polymer container adapted to receive a chromatographic packing material, the container having an outlet port located at a downstream end of the container and configured for connecting to chromatographic equipment during use of the cartridge, the container having container threads formed on an upstream end of the container;   a polymer cap having an inlet port located on an upstream end of the container, the port being configured for connecting to chromatographic equipment during use of the cartridge, the cap having cap threads located on the cap to threadingly engage the container threads;   a resilient fluid tight seal interposed between the cap and container suitable for use in low pressure liquid chromatography; and   a locking tab on a skirt of the cap, the locking tab being located and configured to engage a recess on the container when the seal engages the cap and container to lock the cap in position   
     
     
         2 .- 10 . (canceled) 
     
     
         11 . A low pressure liquid chromatography cartridge, comprising:
 a tubular polymer container adapted to receive a chromatographic packing material, the container having an outlet port located at a downstream end of the container and configured for use with chromatographic equipment during use of the cartridge, the container having container threads formed on an upstream end of the container;   a polymer cap having an inlet port located on an upstream end of the cap, the port being configured for use with chromatographic equipment during use of the cartridge, the cap having cap threads located on the cap to threadingly engage the container threads; and   resilient sealing means baying inclined surfaces for sealing the cap to the container when a user places the cap on the container and engages the locking means.   
     
     
         12 .- 13 . (canceled) 
     
     
         14 . A method for a user to perform low pressure liquid chromatography, comprising:
 placing at least one of a material to be analyzed or a chromatographic packing material in a tubular polymer container haying an outlet port located at a downstream end of the container and configured for use with chromatographic equipment, the container having container threads formed on an upstream end of the container;   threadingly engaging threads on a polymer cap with the container threads, the cap haying an inlet port on an upstream end of the cap; and   sealing the cap to the container by tightening the threads and engaging a seal having inclined surfaces between the cap and the container, the seal providing a fluid tight seal below about 100 psi suitable for LPLC use.   
     
     
         15 .- 22 . (canceled)