US2017028018A1PendingUtilityA1
Irisin for care and prevention of osteoporosis
Assignee: UNIVERSITA' DEGLI STUDI DI BARIPriority: Apr 16, 2015Filed: Apr 14, 2016Published: Feb 2, 2017
Est. expiryApr 16, 2035(~8.7 yrs left)· nominal 20-yr term from priority
Inventors:Maria GranoGraziana ColaianniConcetta CuscitoGiacomina BrunettiSilvia ColucciSaverio CintiGiorgio Mori
A61P 19/00A61P 19/10A61K 38/17A61K 38/22
21
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Claims
Abstract
Object of the present invention is the use of Irisin for the treatment and/or prevention of osteoporosis. In particular, the present invention refers to the use of recombinant irisin for the treatment and/or prevention of osteoporosis.
Claims
exact text as granted — not AI-modified1 . Irisin for use in the treatment and/or prevention of osteoporosis.
2 . The irisin for use according to claim 1 , wherein said irisin is recombinant irisin.
3 . The irisin for use according to claim 2 , wherein said recombinant irisin comprises the amino acid sequence:
(SEQ. ID NO. 1)
DSPSAPVNVTVRHLKANSAVVSWDVLEDEVVIGFAISQQKKDVRM
LRFIQEVNTTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPR
EAEKMASKNKDEVTMKE.
4 . The irisin for use according to claim 1 , wherein a dosage of said irisin is between 500 μg/kg and 50 μg/kg.
5 . The irisin for use according to claim 1 , wherein a dosage of said irisin is between 250 μg/kg and 75 μg/kg.
6 . The irisin for use according to claim 1 , wherein a dosage of said irisin is 100 μg/kg.
7 . Compositions comprising irisin for use in the treatment and/or prevention of osteoporosis.
8 . The compositions for use according to claim 7 , wherein said irisin is recombinant irisin.
9 . The compositions for use according to claim 8 , wherein said recombinant irisin comprises the amino acid sequence:
(SEQ. ID NO. 1)
DSPSAPVNVTVRHLKANSAVVSWDVLEDEVVIGFAISQQKKDVRM
LRFIQEVNTTTRSCALWDLEEDTEYIVHVQAISIQGQSPASEPVLFKTPR
EAEKMASKNKDEVTMKE.
10 . The compositions for use according to claim 7 , wherein said irisin comprises excipients and/or additives for pharmaceutical use.Join the waitlist — get patent alerts
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