Bioerodable metallic stent with biodegradable polymer coating

Abstract

A device and a method of manufacturing an implantable medical device, such as a stent, are described herein. The device includes a metallic region composed of a bioerodable metal and a polymer region composed of a biodegradable polymer contacting the metallic region. The metallic region may erode at a different rate when exposed to bodily fluids than the polymer region when exposed to bodily fluids. In certain embodiments, the polymer region is an outer layer and the metallic region is an inner layer of the device.

1 . A stent comprising:
 struts made of a metal comprising magnesium; and   a coating on the struts, wherein the coating comprises a biodegradable polymer and a drug, wherein the biodegradable polymer is selected from the group consisting of poly(L-lactic acid) and poly(D,L-lactic acid), and wherein the struts have surfaces and the coating completely covers the surfaces of the struts.   
     
     
         2 . (canceled) 
     
     
         3 . (canceled) 
     
     
         4 . (canceled) 
     
     
         5 . (canceled) 
     
     
         6 . A stent comprising a scaffolding including a pattern of interconnecting struts, wherein a cross section of a strut of the struts includes a core and a coating around the core, wherein the core is made of a bioerodible metal and the coating comprises a biodegradable polymer and a drug, wherein the biodegradable polymer is selected from the group consisting of poly(L-lactic acid), poly(D,L-lactic acid), and poly(lactide-co-glycolide). 
     
     
         7 . The stent of  claim 6 , wherein the bioerodible metal is an alloy and comprises magnesium. 
     
     
         8 . (canceled) 
     
     
         9 . (canceled) 
     
     
         10 . (canceled) 
     
     
         11 . The stent of  claim 6 , wherein upon implantation of the stent in a vessel, the core is configured to erode when erosion of the coating exposes a portion of the core to bodily fluids. 
     
     
         12 . The stent of  claim 6 , wherein upon implantation of the stent in a vessel, the coating inhibits or prevents direct contact or exposure of the core to a vascular environment. 
     
     
         13 - 18 . (canceled) 
     
     
         19 . The stent of  claim 1 , wherein the metal is an alloy.