Method and Composition for Oral Health Care Treatment

Abstract

A method for oral health treatment of a subject using a composition having an anti-oxidant enzyme, an anti-inflammatory agent, and a pharmaceutically acceptable buffer. In certain embodiments, the compositions are administered to the subject in conjunction with teeth whitening, oral surge oral pathology treatment, endodontic therapy, periodontal therapy, dental restoration, preventative tooth cleaning, or subsequent to a pro-oxidant.

What is claimed is: 
     
         1 . A method for educing an elevated free radical concentration in an oral cavity of a subject, comprising administering to the subject's oral cavity a composition comprising (a) an effective amount of an anti-oxidant enzyme, wherein the anti-oxidant enzyme is catalase; (b) an effective amount of an anti-inflammatory agent; and (c) a pharmaceutically acceptable buffer, whereby an elevated free radical concentration in the oral cavity of the subject is reduced. 
     
     
         2 . The method of  claim 1 , wherein the composition is provided to the subject in conjunction with a dental procedure. 
     
     
         3 . The method of  claim 2 , wherein the dental procedure is selected from the group consisting of teeth whitening, oral surgery, oral pathology treatment, endodontic therapy, periodontal therapy, dental restoration, general preventative tooth cleaning, a pro-oxidant treatment, internal or external dental bleaching, tooth extraction, hard or soft tissue surgery, root canal therapy, apical surgery, debridement, scaling, root planing, composite or bonding procedure, and a prophylactic procedure. 
     
     
         4 . The method of  claim 1 , wherein the anti-inflammatory agent is selected from the group consisting of an extract of pomegranate, cranberry, acai berry, rooibos, green tea, avocado, and mixtures thereof. 
     
     
         5 . The method of  claim 1 , wherein the composition further comprises a reducing agent selected from the group consisting of vitamin C and vitamin E. 
     
     
         6 . The method of  claim 1 , wherein the composition further comprises an anti-cavity agent. 
     
     
         7 . The method of  claim 1 , wherein the composition further comprises an anti-sensitivity agent. 
     
     
         8 . A method for educing an elevated free radical concentration in an oral cavity of a subject, comprising administering to the subject's oral cavity a composition comprising (a) an effective amount of an anti-oxidant; (b) an effective amount of an anti-inflammatory agent, wherein the anti-inflammatory agent is an extract of pomegranate; and (c) a pharmaceutically acceptable buffer, whereby an elevated free radical concentration in the oral cavity of the subject is reduced. 
     
     
         9 . The method of  claim 8 , wherein the composition is provided to the subject in conjunction with a dental procedure. 
     
     
         10 . The method of  claim 9  wherein the dental procedure is selected from the group consisting of teeth whitening, oral surgery, oral pathology treatment, endodontic therapy, periodontal therapy, dental restoration, general preventative tooth cleaning, a pro-oxidant treatment, internal or external dental bleaching, tooth extraction, hard or soft tissue surgery, root canal therapy, apical surgery, debridement, scaling, root planing, composite or bonding procedure, and a prophylactic procedure. 
     
     
         11 . The method of  claim 8 , wherein the anti-oxidant is selected from the group consisting of catalase, superoxide dismutase, methionine reductase, glutathione peroxidase, superoxide reductase, peroxidase, and mixtures thereof. 
     
     
         12 . The method of  claim 8 , wherein the composition further comprises a reducing agent selected from the group consisting of vitamin C and vitamin E. 
     
     
         13 . The method of  claim 8 , wherein the composition further comprises an anti-cavity agent. 
     
     
         14 . The method of  claim 8 , wherein the composition further comprises anti-sensitivity agent. 
     
     
         15 . A method for reducing an elevated free radical concentration in an oral cavity of a subject, comprising administering to the subject's oral cavity a composition comprising (a) an effective amount of an anti-oxidant enzyme selected from the group consisting of catalase, methionine reductase, superoxide reductase, and mixtures thereof; (b) an effective amount of an anti-inflammatory agent; and (c) a pharmaceutically acceptable buffer, whereby an elevated free radical concentration in the oral cavity of the subject is reduced. 
     
     
         16 . The method of  claim 15 , wherein the composition is provided to the subject in conjunction with a dental procedure. 
     
     
         17 . The method of  claim 15 , wherein the anti-inflammatory agent is selected from the group consisting of an extract of pomegranate, cranberry, acai berry, rooibos, green tea, avocado, and mixtures thereof. 
     
     
         18 . The method of  claim 15 , wherein the composition further comprises a reducing agent selected from the group consisting of vitamin C and vitamin E. 
     
     
         19 . The method of  claim 15 , wherein the composition further comprises an anti-cavity agent. 
     
     
         20 . The method of  claim 5 , wherein the composition further comprises an anti-sensitivity agent.