US2017000824A1PendingUtilityA1

Drug delivery compositions and methods

51
Assignee: RAZAVI ALIPriority: Apr 2, 2014Filed: Sep 16, 2016Published: Jan 5, 2017
Est. expiryApr 2, 2034(~7.7 yrs left)· nominal 20-yr term from priority
Inventors:Ali Razavi
A61L 2300/214A61P 17/02A61K 31/16A61K 31/198A61L 15/44A61K 33/40A61K 9/14A61K 9/16A61L 15/18A61L 15/20A61L 2300/404A61K 9/7007A61L 15/64A61K 9/0014A61L 2300/11
51
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Claims

Abstract

A drug delivery composition is disclosed which includes a triple salt proxy functional group and at least one amino acid functional group. A method of forming the drug delivery composition includes reacting a triple salt with at least one amino acid in an aqueous environment. A biodegradable fabric is disclosed which includes a polymerized structure of a triple salt proxy functional group and at least one amino acid functional group.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A drug delivery composition comprising a triple salt proxy functional group and at least one amino acid functional group, wherein the triple salt proxy functional group includes a peroxy moiety. 
     
     
         2 . The drug delivery composition of  claim 1 , wherein the triple salt proxy functional group is K + HSO 5   − . 
     
     
         3 . The drug delivery composition of  claim 1 , wherein the amino acid functional group is selected from the group consisting of derivatives of glutamine, alanine, aspartic acid, lysine, glycine, cysteine, arginine, proline, naturally occurring peptides, artificially occurring peptides, and combinations thereof. 
     
     
         4 . The drug delivery composition of  claim 1 , wherein the triple salt proxy functional group includes the property of broad spectrum antimicrobial activities against bacteria, fungi and viruses. 
     
     
         5 . The drug delivery composition of  claim 1 , wherein the drug delivery composition further comprises a plurality of amino acid functional groups. 
     
     
         6 . The drug delivery composition of  claim 5 , wherein the plurality of amino acid functional groups further comprises amino acid health benefits. 
     
     
         7 . The drug delivery composition of  claim 1 , wherein the drug delivery composition is a powder base material. 
     
     
         8 . The drug delivery composition of  claim 7 , wherein the powder base material further comprises the property of rapid solubility in an aqueous solution. 
     
     
         9 . A method for forming a drug delivery composition comprising reacting a triple salt including a peroxy moiety with at least one amino acid in an aqueous environment, wherein the drug delivery composition includes a triple salt proxy functional group and at least one amino acid functional group, the triple salt proxy functional group including the peroxy moiety. 
     
     
         10 . The method of  claim 9 , wherein the triple salt is potassium peroxymonosulfate. 
     
     
         11 . The method of  claim 9 , wherein the at least one amino acid is selected from the group consisting of glutamine, alanine, aspartic acid, lysine, glycine, cysteine, arginine, proline, naturally occurring peptides, artificially occurring peptides, and combinations thereof. 
     
     
         12 . The method of  claim 9 , further comprising reacting the triple salt with a plurality of amino acids in the aqueous environment. 
     
     
         13 . The method of  claim 9 , wherein the triple salt proxy functional group further comprises the property of broad spectrum antimicrobial activities against bacteria, fungi and viruses. 
     
     
         14 . The method of  claim 9 , wherein the drug delivery composition further comprises amino acid health benefits. 
     
     
         15 . The method of  claim 9 , further comprising treating an individual having a wound with the drug delivery composition. 
     
     
         16 . A biodegradable fabric comprising a polymerized structure of a triple salt proxy functional group and at least one amino acid functional group, wherein the triple salt proxy functional group includes a peroxy moiety. 
     
     
         17 . The biodegradable fabric of  claim 16 , wherein the triple salt proxy functional group is K − HSO 5   − . 
     
     
         18 . The biodegradable fabric of  claim 16 , wherein the amino acid functional group is selected from the group consisting of derivatives of glutamine, alanine, aspartic acid, lysine, glycine, cysteine, arginine, proline, naturally occurring peptides, artificially occurring peptides, and combinations thereof 
     
     
         19 . The biodegradable fabric of  claim 16 , wherein the polymerized structure further comprises the property of broad spectrum antimicrobial activities against bacteria, fungi and viruses. 
     
     
         20 . The biodegradable fabric of  claim 16 , wherein the polymerized structure further comprises amino acid health benefits.

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