Formulations comprising saponins and uses thereof

Abstract

Provided is a formulation including various natural extracts for a variety of human applications.

1 .- 49 . (canceled) 
     
     
         50 . A composition comprising an anti-bacterially effective amount of a saponin material and an anti-bacterially effective amount of a plant extract from at least one plant selected from the group consisting of  Lonicera, Populus , and  Wasabia  or a mixture thereof,
 wherein the saponin material is obtained from a plant source selected from the group consisting of shikakai, soyabeans, beans, peas ( Pisum sativum ), lucerne, tea, spinach, sugar beet,  quinoa , liquorice, sunflower, horse chestnut,  ginseng , oats,  capsicum  peppers, aubergine, tomato seed, alliums, asparagus, yam, fenugreek,  yucca  and  ginseng , lucerne, mung beans,  Bupleurum falcatum, Camellia oleifera, Camellia sinensis Desmodium adscendens, Gypsophila, Panax quinqufolius, Panax japonicas, Quillaja saponaria, Sapindus delavayi, Sapindus mukorossi, Sapindus marginatus, Sapindus saponaria, Sapindus trifoliatus, Saponaria officinalis, Styrax japonica , and  Yucca schidigera  or any mixture thereof.   
     
     
         51 . The composition according to  claim 50 , wherein the saponin material is obtained from a plant source selected from the group consisting of  Camellia sinensis, Camellia oleifera, Saponaria officinalis , and  Sapindus mukorossi  or a mixture thereof. 
     
     
         52 . The composition according to  claim 50 , wherein the saponin material is selected from the group consisting of a saponin-containing extract or a saponin compound obtained from the at least one plant selected from the group consisting of  Camellia sinensis, Camellia oleifera, Saponaria officinalis , and  Sapindus mukorossi  or a mixture thereof. 
     
     
         53 . The composition according to  claim 50 , wherein the weight ratio between the saponin material and the plant extract is between about 1:100 and about 100:1. 
     
     
         54 . The composition according to  claim 50 , wherein the saponin-containing extract is obtained by extraction of said plant with water, alcohol, or a water/alcohol mixture. 
     
     
         55 . The composition according to  claim 54 , wherein the water/alcohol mixture has a water:alcohol ratio selected from a ratio of between 80:20 and 20:80, a ratio of between 60:40 and 40:60, a ratio of between 70:30 and 30:70, and a ratio of 50:50, respectively. 
     
     
         56 . The composition according to  claim 50 , wherein the saponin-containing extract is extracted from said plant by a method comprising:
 a) extracting the plant in a water:alcohol solution having a water:alcohol ratio of between 40:60 and 60:40 for a suitable period of time;   b) optionally, evaporating the extract to a obtain a solid saponin-containing extract; and   c) optionally, purifying one or more saponin compounds from said solid saponin-containing extract.   
     
     
         57 . The composition according to  claim 56 , wherein the water:alcohol ratio is 50:50. 
     
     
         58 . The composition according to  claim 57 , wherein the plant is  Camellia oleifera  or  Sapindus mukorossi.    
     
     
         59 . The composition according to  claim 50 , wherein the  Lonicera  extract is an extract of  Lonicera japonica.    
     
     
         60 . The composition according to  claim 50 , wherein the  Populus  extract is an extract of aspen. 
     
     
         61 . The composition according to  claim 60 , wherein the extract is of  Populus tremuloides.    
     
     
         62 . The composition according to  claim 50 , wherein the  Wasabia  extract is an extract of  Wasabia japonica.    
     
     
         63 . The composition according to  claim 50 , wherein the weight ratio between the saponin material and the plant extract is between about 1:1 and about 10:1, respectively. 
     
     
         64 . A product comprising an anti-bacterially effective amount of the composition of  claim 50 , wherein the product is selected from the group consisting of a preservative formulation, an antimicrobial formulation, a pharmaceutical composition, a disinfectant, and a cosmetic product. 
     
     
         65 . A soap comprising an anti-bacterially effective amount of the composition of  claim 50 . 
     
     
         66 . An add-on formulation comprising an anti-bacterially effective amount of the composition of  claim 50 , wherein the add-on formulation is suitable for adding into a product selected from the group consisting of a preservative formulation, an antimicrobial formulation, a pharmaceutical composition, a disinfectant, and a cosmetic product.