Organization, visualization and utilization of genomic data on electronic devices

Abstract

Described herein are methods, devices and systems for simple organization, visualization and use of genome data (e.g. human genome data) on electronic devices (e.g. portable devices). In some embodiments, the data are organized and/or visualized according to phenotype traits, genes, and/or markers in a similar manner to the organization and/or visualization of digital music contents. This concept allows a new procedure for genomic data organization and facilitates the development of genomic data visualization tools. The methods described herein can be implemented with consumer-oriented software on electronic devices, computers, and portable devices, for the use of genomic related data in the field of personalized medicine for predictive, preventive and participative wireless healthcare.

What is claimed is: 
     
         1 . A graphical user interface (GUI) for displaying genomic information on a mobile device, the GUI comprising:
 (a) a listing of phenotypic traits, diseases, or a combination thereof;   (b) a listing of genes; and   (c) a listing of genetic markers, wherein the genetic markers comprise metadata comprising:
 (i) a default map location; 
 (ii) a nucleotide UID; and 
 (iii) a gene ontology, 
   whereby selecting a phenotypic trait or disease from list (a) displays a listing of genes and/or genetic markers correlated with the selected phenotypic trait or disease.   
     
     
         2 . The GUI of  claim 1 , wherein the metadata further comprises one or more of: a disease name, a phenotype, a gene name, a protein name, a chromosome, a nucleotide accession, a protein accession, a protein UID, a EC/RN number, a filter, a locus link ID, a MIM, a modification date, a property, a PubMed UID, a taxonomy ID, a text word, and a UniGene cluster number. 
     
     
         3 . The GUI of  claim 1 , wherein the phenotypic traits, diseases, or a combination thereof are represented by images. 
     
     
         4 . The GUI of  claim 3 , wherein the images further comprise genes and/or genetic markers correlated with the phenotypic trait or disease. 
     
     
         5 . The GUI of  claim 3 , wherein the images are scrollable by touching the display of the mobile device with a vertical, horizontal, or circular motion. 
     
     
         6 . The GUI of  claim 3 , wherein the images further comprise an indication when the phenotypic trait or diseases is clinically relevant in an individual. 
     
     
         7 . The GUI of  claim 6 , wherein the indication is a color code. 
     
     
         8 . The GUI of  claim 1 , wherein the genomic information is from an individual person. 
     
     
         9 . The GUI of  claim 1 , wherein the genomic information is obtained from public databases. 
     
     
         10 . The GUI of  claim 1 , wherein the correlations are obtained from public databases and/or scientific literature. 
     
     
         11 . A method for displaying genomic information on a mobile device, the method comprising populating a multimedia database viewable by a graphical user interface (GUI) with genomic information in place of multimedia information, whereby operation of the GUI displays genomic information. 
     
     
         12 . The method of  claim 11 , wherein:
 (a) an album title field is populated with a listing of phenotypic traits, diseases, or a combination thereof;   (b) an artist field is populated with a listing of genes; and   (c) a title track field is populated with a listing of genetic markers,   whereby selecting a phenotypic trait or disease from list (a) displays a listing of genes and/or genetic markers correlated with the selected phenotypic trait or disease.   
     
     
         13 . The method of  claim 12 , further comprising one or more of:
 (a) activating an application on the mobile device based on the genomic information; and   (b) integrating geolocation information of the mobile device with the genomic information.   
     
     
         14 . A genomic information database structure, wherein the container is a phenotypic trait, disease, or combination thereof, and wherein the database further comprises genes, genetic markers, default map locations, nucleotide UID, and gene ontology information. 
     
     
         15 . A method for creating a portable genomic dataset for an individual, the method comprising:
 (a) obtaining a set of genetic markers of the individual in a computer readable format;   (b) attributing a probability of expression of one or more phenotypic traits for each genetic marker by comparing each genetic marker with a correlation between the phenotypic trait and the genetic marker in a population of individuals;   (c) assembling sets of genetic markers related to each phenotypic trait;   (d) optionally calculating the probability of expression of the phenotype; and   (e) producing a portable genomics data set comprising only the information about phenotypic traits expected to be expressed by the individual, the relevant genetic markers, and the probability of expression of the phenotypic trait.   
     
     
         16 . A portable electronic device configured to display the GUI of  claim 1 . 
     
     
         17 . A portable electronic device configured to perform the method of  claim 11  or  15 . 
     
     
         18 . A portable electronic device comprising the genomic information database structure of  claim 14 . 
     
     
         19 . A portable electronic device encoding the portable genomic dataset of  claim 15 . 
     
     
         20 . The portable electronic device of  claims 16 - 19 , wherein the device is a mobile phone, personal digital assistant (PDA), or tablet computer. 
     
     
         21 . Use of the method of  claim 1  or the portable electronic device of  claim 20  to schedule a medication dosage regimen, and/or monitor compliance thereof. 
     
     
         22 . Use of the method of  claim 1  or the portable electronic device of  claim 20  to share genomic information with medical professionals. 
     
     
         23 . Use of the method of  claim 1  or the portable electronic device of  claim 20  to schedule medical appointments or consult medical specialists. 
     
     
         24 . Use of the method of  claim 1  or the portable electronic device of  claim 20  to facilitate financial transactions based on genomic information. 
     
     
         25 . Use of the method of  claim 1  or the portable electronic device of  claim 20  to predict the efficacy of a drug and/or to predict side-effects of a drug. 
     
     
         26 . Use of the method of  claim 1  or the portable electronic device of  claim 20  in combination with geolocation features of the portable electronic device to determine the relative contribution of genetics and environment on a phenotypic trait or disease. 
     
     
         27 . Use of the method of  claim 1  or the portable electronic device of  claim 20  by two individuals in order to determine the last common ancestor shared by the individuals. 
     
     
         28 . Use of the method of  claim 1  or the portable electronic device of  claim 20  by a male individual and by a female individual in order to determine the probability of phenotypic traits and/or diseases being expressed in the offspring produced by the male and female individuals. 
     
     
         29 . The method of  claim 1 , wherein the genetic markers are single nucleotide polymorphisms (SNPs), micro-satellites, DNA methylation patterns, histone deacetylation patterns, or any combination thereof.