Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities

Abstract

Methods and kits for treating a cardiac arrhythmia using a platelet rich plasma (PRP) composition are provided. Any type of arrhythmia may be treated using the PRP composition. The PRP composition may comprise PRP developed using blood collected from a patient suffering the cardiac arrhythmia. The PRP composition may be buffered to a physiological pH and may include one or more anti-arrhythmic agents, anti-coagulants, or other drugs. The PRP composition may be delivered using a nebulizer, minimally invasively, or surgically.

1 . A method for treating a issue injury, comprising:
 identifying a tissue injury in a patient; and   delivering a platelet rich plasma (PRP) composition to the patient in an amount sufficient to treat the tissue injury, wherein the platelet rich plasma composition is in an inhalable form.   
     
     
         2 - 7 . (canceled) 
     
     
         8 . The method of  claim 1 , wherein the platelet rich plasma composition is prepared from whole blood of the patient. 
     
     
         9 . The method of  claim 1 , wherein the platelet rich plasma composition is buffered to a physiological pH, and wherein the physiological pH is between about 7.3 and about 7.5. 
     
     
         10 . The method of  claim 1 , wherein the inhalable form is an inhalable powder. 
     
     
         11 . (canceled) 
     
     
         12 . The method of  claim 1 , wherein the inhalable form is delivered with a nebulizer or inhaler. 
     
     
         13 . (canceled) 
     
     
         14 . A kit comprising:
 a nebulizer or inhaler comprising platelet rich plasma in an inhalable form.   
     
     
         15 - 20 . (canceled) 
     
     
         21 . The method of  claim 1 , wherein the injured tissue is selected from the group consisting of stomach, abdominal wall, bladder, and vascular tissue. 
     
     
         22 . The method of  claim 1 , wherein the inhalable form is a dry powder. 
     
     
         23 . The method of  claim 1 , wherein the inhalable form is a PRP composition delivered with a nebulizer or inhaler. 
     
     
         24 . A method of preparing platelet rich plasma (PRP) comprising
 isolating platelets; and   drying the isolated platelets.   
     
     
         25 . The method of  claim 24 , wherein the platelets are buffered to a physiological pH, and wherein the physiological pH is between about 7.3 and about 7.5. 
     
     
         26 . A method of preparing PRP in an inhalable form comprising:
 collecting blood from a patient;   isolating platelets from the collected blood;   suspending the isolated platelets in plasma to form a PRP composition;   providing the isolated PRP composition in an inhaler or nebulizer.   
     
     
         27 . The method of  claim 26 , wherein the platelets are isolated by centrifugation. 
     
     
         28 . The method of  claim 26 , wherein the platelet rich plasma composition is buffered to a physiological pH, and wherein the physiological pH is between about 7.3 and about 7.5. 
     
     
         29 . The method of  claim 26 , further comprising leukoreducing the PRP composition. 
     
     
         30 . The method of  claim 26 , further comprising immunoadsorbing the PRP composition.