Composition and dressing for wound treatment

Abstract

The invention provides methods and compositions for wound treatment and/or blood clot formation, e.g., arresting the flow of blood from an open wound. The methods and compositions provide for promoting and accelerating wound healing and optionally provide for inhibition of microbial infection and/or a local analgesic effect.

What is claimed is: 
     
         1 . A composition for wound healing, comprising:
 a substantially homogeneous mixture comprising an amount of mullite, wherein the amount of mullite is effective to promote blood clot formation, and aluminum sulfate,   wherein the composition is in powder or liquid form.   
     
     
         2 . The composition of  claim 1 , further comprising a local anesthetic agent. 
     
     
         3 . The composition of  claim 1 , further comprising an analgesic agent. 
     
     
         4 . The composition of  claim 1 , further comprising an antiseptic agent. 
     
     
         5 . The composition of  claim 4 , wherein the antiseptic agent is an antimicrobial agent. 
     
     
         6 . The composition of  claim 1 , wherein the aluminum sulfate and mullite are present in a ratio of at least 1:3 by volume. 
     
     
         7 . The composition of  claim 1 , wherein the aluminum sulfate and mullite are present in a ratio of at least 1:2 by volume. 
     
     
         8 . The composition of  claim 1 , wherein the aluminum sulfate and mullite are present in a ratio of at least 1:1 by volume. 
     
     
         9 . A hemostatic device comprising a wound dressing and the composition of  claim 1 . 
     
     
         10 . The hemostatic device of  claim 9 , wherein the wound dressing is a bandage. 
     
     
         11 . A method for promoting blood clot formation, comprising:
 providing a composition in powder or liquid form, the composition comprising a substantially homogeneous mixture comprising an amount of mullite, wherein the amount of mullite is effective to promote blood clot formation, and aluminum sulfate; and   contacting a wound on the skin of a mammal with the composition.   
     
     
         12 . The method of  claim 11 , wherein the composition further comprises a local anesthetic agent. 
     
     
         13 . The method of  claim 11 , wherein the composition further comprises an analgesic agent. 
     
     
         14 . The method of  claim 11 , wherein the composition further comprises an antiseptic agent. 
     
     
         15 . The method of  claim 14 , wherein the antiseptic agent is an antimicrobial agent. 
     
     
         16 . The method of  claim 11 , wherein the aluminum sulfate and mullite in the composition are present in a ratio of at least 1:3 by volume. 
     
     
         17 . The method of  claim 11 , wherein the aluminum sulfate and mullite in the composition are present in a ratio of at least 1:2 by volume. 
     
     
         18 . The method of  claim 11 , wherein the aluminum sulfate and mullite in the composition are present in a ratio of at least 1:1 by volume. 
     
     
         19 . The method of  claim 11 , wherein the composition is applied to a wound dressing prior to contacting the wound on the skin of the mammal with the composition. 
     
     
         20 . The method of  claim 19 , wherein the wound dressing is a bandage.