US2016312186A1PendingUtilityA1

Non-biologic surgical implant

Assignee: P TECH LLCPriority: Jun 7, 2002Filed: Jun 16, 2016Published: Oct 27, 2016
Est. expiryJun 7, 2022(expired)· nominal 20-yr term from priority
C12N 5/0062C12N 2501/10C12N 2533/90C12N 5/0691Y10S623/92A61F 2/02A61L 24/0015A61F 2002/2835A61L 24/08C12N 2501/11A61F 2/28A61F 2210/0004C12N 2501/105C12N 2533/54C12N 5/0068C12N 2501/155A61F 2/0077A61F 2/4601C12N 2513/00C12N 2501/135A61F 2002/2817C12N 5/0654
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Claims

Abstract

A method of creating a non-biologic implant configured for implantation into a patient is provided. The method includes constructing a non-biologic three dimensional composite support structure integrally formed as one piece, the non-biologic three dimensional composite support structure including a nonbiodegradable material and having a porous construction with a plurality of passages, wherein the support structure is constructed to have a configuration corresponding to at least one of a bone and a portion of a bone to be replaced in the patient. The method also includes providing the non-biologic three dimensional composite support structure to enable placement of the non-biologic three dimensional composite support structure in the patient, wherein an outer surface of the support structure is configured to be pressed adjacent the bone, wherein the non-biologic three dimensional composite support structure is configured to be positioned in the body to promote growth of tissue in the body of the patient into at least a portion of the non-biologic three dimensional composite support structure by having at least a portion of the porous construct adjacent the bone enabling biologic structures to grow into the plurality of passages in the porous construction to securely connect the support structure in place in the body of the patient.

Claims

exact text as granted — not AI-modified
1 . A method of creating a non-biologic surgical implant configured for implantation onto a portion of a bone of a patient, the method comprising:
 constructing a non-biologic three dimensional composite support structure integrally formed as one piece, the non-biologic three dimensional composite support structure including a nonbiodegradable material and having a porous construction with a plurality of passages, wherein the support structure is constructed to have a configuration corresponding to at least one of a bone and a portion of a bone to be replaced in the patient; and   providing the non-biologic three dimensional composite support structure to enable placement of the non-biologic three dimensional composite support structure in the patient, wherein an outer surface of the support structure is configured to be pressed adjacent the bone,   wherein the non-biologic three dimensional composite support structure is configured to be positioned in the body to promote growth of tissue in the body of the patient into at least a portion of the non-biologic three dimensional composite support structure by having at least a portion of the porous construct adjacent the bone enabling biologic structures to grow into the plurality of passages in the porous construction to securely connect the support structure in place in the body of the patient.   
     
     
         2 . The method according to  claim 1 , wherein the non-biologic three dimensional composite support structure may be configured to be positioned in the patient by a surgical robotic mechanism. 
     
     
         3 . The method according to  claim 1 , wherein the non-biologic three dimensional composite support structure may be constructed of different materials. 
     
     
         4 . The method according to  claim 1 , wherein viable cells may be layered on the non-biologic three dimensional composite support structure. 
     
     
         5 . The method according to  claim 4 , wherein the viable cells include cells that are at least one of fibroblast cells, osteochondral cells, osteoblast cells, osteoclast cells, mesodermal cells, and myoblast cells. 
     
     
         6 . The method according to  claim 1 , wherein the tissue growth promoted by the non-biologic three dimensional composite support structure is at least one of bone, cartilage, and muscle. 
     
     
         7 . The method according to  claim 1 , wherein osteoinductive growth factors including at least one of IGF (insulin-like growth factors), TGF (transforming growth factors), FGB (fibroblast growth factors), EGF (epidermal growth factors), BMP (bone morphogenic proteins), and PDGF (platelet-derived growth factors) may be added to the non-biologic three dimensional composite support structure. 
     
     
         8 . The method according to  claim 1 , wherein at least one type of antibiotic may be added to the non-biologic three dimensional composite support structure. 
     
     
         9 . A non-biologic implant for replacing at least a portion of a bone of a patient, the non-biologic implant comprising:
 a non-biologic three dimensional composite support structure integrally formed as one piece, the non-biologic three dimensional composite support structure including a nonbiodegradable material and having a porous construction with a plurality of passages,   wherein the non-biologic three dimensional composite support structure is constructed to have a configuration corresponding to at least one of a bone and a portion of a bone to be replaced in a patient,   wherein the non-biologic three dimensional composite support structure is configured to promote growth when an outer surface of the porous support structure is positioned adjacent the bone, and   wherein the non-biologic three dimensional composite support structure is configured to be positioned in the body to promote growth of tissue in the body of the patient into at least a portion of the non-biologic three dimensional composite support structure by having at least a portion of the porous construct adjacent the bone, enabling biologic structures to grow into the plurality of passages in the porous construction to securely connect the support structure in place in the body of the patient.   
     
     
         10 . The non-biologic implant according to  claim 9 , wherein the non-biologic three dimensional composite support structure may be configured to be positioned in the patient by a surgical robotic mechanism. 
     
     
         11 . The non-biologic implant according to  claim 9 , wherein the non-biologic three dimensional composite support structure may be constructed of different materials. 
     
     
         12 . The non-biologic implant according to  claim 9 , wherein viable cells may be layered on the non-biologic three dimensional composite support structure. 
     
     
         13 . The non-biologic implant according to  claim 12 , wherein the viable cells include cells that are at least one of fibroblast cells, osteochondral cells, osteoblast cells, osteoclast cells, mesodermal cells, and myoblast cells. 
     
     
         14 . The non-biologic implant according to  claim 9 , wherein the tissue growth is promoted by the non-biologic three dimensional composite support structure is at least one of bone, cartilage, and muscle. 
     
     
         15 . The non-biologic implant according to  claim 9 , wherein osteoinductive growth factors including at least one of IGF (insulin-like growth factors), TGF (transforming growth factors), FGB (fibroblast growth factors), EGF (epidermal growth factors), BMP (bone morphogenic proteins), and PDGF (platelet-derived growth factors) may be added to the non-biologic three dimensional composite support structure. 
     
     
         16 . The non-biologic implant according to  claim 9 , wherein at least one type of antibiotic may be added to the non-biologic three dimensional composite support structure. 
     
     
         17 . A non-biologic implant for replacing at least a portion of an organ of a patient, the non-biologic implant comprising:
 a non-biologic three dimensional composite support structure integrally formed as one piece, the non-biologic three dimensional composite support structure including a nonbiodegradable material and having a porous construction with a plurality of passages,   wherein the non-biologic three dimensional composite support structure is constructed to have a configuration corresponding to at least one of an organ and a portion of an organ to be replaced in a patient,   wherein the non-biologic three dimensional composite support structure is configured to promote growth when an outer surface of the porous support structure is positioned adjacent the organ, and   wherein the non-biologic three dimensional composite support structure is configured to be positioned in the body to promote growth of tissue in the body of the patient into at least a portion of the non-biologic three dimensional composite support structure by having at least a portion of the porous construct adjacent the organ, enabling biologic structures to grow into the plurality of passages in the porous construction to securely connect the support structure in place in the body of the patient.   
     
     
         18 . The non-biologic implant according to  claim 17 , wherein the non-biologic three dimensional composite support structure may be configured to be positioned in the patient by a surgical robotic mechanism. 
     
     
         19 . The non-biologic implant according to  claim 17 , wherein the non-biologic three dimensional composite support structure may be constructed of different materials. 
     
     
         20 . The non-biologic implant according to  claim 17 , wherein viable cells may be layered on the synthetic three dimensional composite support structure. 
     
     
         21 . The non-biologic implant according to  claim 17 , wherein the tissue growth promoted by the non-biologic three dimensional composite support structure is at least one of kidney, pancreas, and heart tissue. 
     
     
         22 . The non-biologic implant according to  claim 17 , wherein at least one type of antibiotic may be added to the non-biologic three dimensional composite support structure.

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