Synthetic milk compositions for optimal growth and development and prevention of obesity in male and female infant and children

Abstract

The invention concerns synthetic nutritional compositions for infants and young children up to the age of thirty-six months, particularly infant formulae and growing-up milks. The compositions vary according to gender and the age of the infant or young child. The compositions of the present invention have been designed to ensure balanced growth and to prevent obesity in infancy and later in life.

1 . A synthetic nutritional composition for infants comprising:
 60-85 kcal/100 ml energy;   3.9-6 g/100 ml lipid; and   600-810 mg/100 ml linoleic acid,   wherein the composition is especially adapted to the nutritional needs of a male infant or child.   
     
     
         2 . The synthetic nutritional composition of  claim 1 , wherein the composition also comprises:
 710-930 mg/100 ml total polyunsaturated acids.   
     
     
         3 . The synthetic nutritional composition of  claim 1 , wherein the composition also comprises a phospholipid selected from the group consisting of:
 4.7-6.8 mg/100 ml of phosphatidylcholine;   6.3-10 mg/100 ml of phosphatidylethanolamine; and   1-2 mg/100 ml of phosphatidylinositol.   
     
     
         4 . The synthetic nutritional composition of  claim 1 , wherein the composition also comprises:
 21-30 mg/100 ml of phospholipids.   
     
     
         5 . The synthetic nutritional composition of  claim 1 , wherein the composition comprises:
 60-75 kcal/100 ml energy;   3.9-4.9 g/100 ml lipid; and   600-740 mg/100 ml linoleic acid;   and further comprises a component selected from the group consisting of:   710-880 mg/100 ml total polyunsaturated acids,   5.4-6.8 mg/100 ml of phosphatidylcholine,   6.3-10 mg/100 ml of phosphatidylethanolamine,   1-1.3 mg/100 ml of phosphatidylinositol, and   21-26 mg/100 ml of phospholipids,   and wherein the composition is especially adapted to a male infant of less than three months old.   
     
     
         6 . The synthetic nutritional composition of  claim 1 , wherein the composition comprises:
 70-85 kcal/100 ml energy;   5.0-6 g/100 ml lipid; and   660-810 mg/100 ml linoleic acid,   and further comprises a component selected from the group consisting of:   755-930 mg/100 ml total polyunsaturated acids,   4.77-5.8 mg/100 ml of phosphatidylcholine,   6.3-10 mg/100 ml of phosphatidylethanolamine,   1.6-1.98 mg/100 ml of phosphatidylinositol, and   24-30 mg/100 ml of phospholipids,   and wherein the composition is especially adapted to a male infant or young boy of more than three months old.   
     
     
         7 . A synthetic nutritional composition for infants comprising:
 57-70 kcal/100 ml energy;   3.5-4.5 g/100 ml lipid; and   410-580 mg/100 ml linoleic acid,   wherein the composition is especially adapted to the nutritional needs of a female infant or child.   
     
     
         8 . The synthetic nutritional composition of  claim 5 , wherein the composition also comprises:
 polyunsaturated acids 510-680 mg/100 ml.   
     
     
         9 . The synthetic nutritional composition of  claim 7 , wherein the composition also comprises a phospholipid selected from the group consisting of:
 5.2-6.4 mg/100 ml of phosphatidylcholine;   5.8-8 mg/100 ml of phosphatidylethanolamine; and   0.9-1.7 mg/100 ml of phosphatidylinositol.   
     
     
         10 . The synthetic nutritional composition of  claim 7 , wherein the composition also comprises:
 19-25 mg/100 ml of phospholipids.   
     
     
         11 . The synthetic nutritional composition of  claim 7 , wherein the composition comprises:
 56-71 kcal/100 ml energy;   3.6-4.4 g/100 ml lipid; and   415-510 mg/100 ml linoleic acid,   and further comprises a component selected from the group consisting of:   510-630 mg/100 ml total polyunsaturated acids;   5.2-6.4 mg/100 ml of phosphatidylcholine;   5.8-7.2 mg/100 ml of phosphatidylethanolamine;   0.9-1.1 mg/100 ml of phosphatidylinositol; and   20-24 mg/100 ml of phospholipids,   and wherein the composition is especially adapted to a female infant of less than three months old.   
     
     
         12 . The synthetic nutritional composition of  claim 7 , wherein the composition comprises:
 56-71 kcal/100 ml energy;   3.6-4.3 g/100 ml lipid; and   475-580 mg/100 ml linoleic acid,   and further comprises a component selected from the group consisting of:   550-670 mg/100 ml total polyunsaturated acids,   5.2-6.4 mg/100 ml of phosphatidylcholine,   6.4-7.9 mg/100 ml of phosphatidylethanolamine,   1.35-1.65 mg/100 ml of phosphatidylinositol, and   20-24 mg/100 ml of phospholipids,   and wherein the composition is especially adapted to a female infant or young girl of more than three months old and less than 36 months old.   
     
     
         13 . A set of synthetic nutritional compositions for infants wherein: a first composition comprises
 60-85 kcal/100 ml energy;   3.9-6 g/100 ml lipid; and   600-810 mg/100 ml linoleic acid;   and a second composition comprises   57-70 kcal/100 ml energy;   3.5-4.5 g/100 ml lipid; and   410-580 mg/100 ml linoleic acid,   the first composition is especially adapted to the nutritional needs of a male infant or child and the second composition is especially adapted to the nutritional needs of a female infant or child.   
     
     
         14 . The synthetic nutritional compositions according to  claim 1 , wherein the composition is in a form selected from the group consisting of an infant formula in the form of a powder, liquid or concentrated liquid, or is a human milk fortifier. 
     
     
         15 . A method for ensuring balanced growth in male infants and young boys and preventing obesity in the male infants and young boys now and later in life comprising administering a synthetic composition comprising
 60-85 kcal/100 ml energy;   3.9-6 g/100 ml lipid; and   600-810 mg/100 ml linoleic acid.   
     
     
         16 . A method for ensuring balanced growth in female infants and young girls and preventing obesity in the female infants and young girls now and later in life comprising administering a synthetic composition comprising
 57-70 kcal/100 ml energy;   3.5-4.5 g/100 ml lipid; and   410-580 mg/100 ml linoleic acid.   
     
     
         17 . (canceled)